Population Exposure-Response Models of Apomorphine Sublingual Film in Healthy Subjects and Patients With Parkinson’s Disease and “OFF” Episodes
Objective: Exposure-response models were developed to characterize the relationship between apomorphine exposure and (1) efficacy using Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease…NS-PARK cohort: a nationwide real life longitudinal cohort of PD patients
Objective: To describe the Parkinson disease (PD) population followed by the 25 expert centers for PD in France. Background: NS-PARK is the clinical research network…Assessing the validity and reliability of MANAGE-PD tool to identify patients with Parkinson’s disease inadequately controlled on oral medications – Results from an international survey of general neurologists and movement disorder specialists
Objective: To evaluate the validity and reliability of MANAGE-PD tool. Background: Timely identification of advancing symptoms in patients with Parkinson’s Disease (PD), thereby improving opportunities…OPICAPONE: REAL WORLD EVIDENCE IN TOLEDO´S MOVEMENT DISORDERS UNIT
Objective: We present a prospective observational-real life study about the use in Movement Disorders Unit´s patients, since its commercialization in Spain (June 2017). Background: The…Population Exposure-Response Modeling of the Effects of Apomorphine Sublingual Film on QTc in Patients With Parkinson’s Disease and “OFF” Episodes
Objective: To characterize the relationship between plasma apomorphine concentrations and QTc (QT interval corrected for heart rate) in patients with Parkinson’s disease (PD) and “OFF”…Deep Brain Stimulation as a Rescue When Duodenal Levodopa Infusion Fails: Report of 2 Cases
Objective: To describe two cases of patients with Parkinson’s disease (PD) where deep brain stimulation (DBS) was used a rescue therapy when duodenal levodopa infusion…Gastrointestinal symptoms as a risk factor for the appearance of motor fluctuations in patients with advanced Parkinson disease
Objective: Gastrointestinal alterations in patients with Parkinson`s Disease (EP) provoke alterations in the absorption of levodopa that facilitates the development of motor fluctuations. Study the…Safinamide: real world evidence in Toledo´s Movement Disorders Unit
Objective: We present a prospective observational-real life study about the use of safinamide in Movement Disorders Unit´s patients. Background: The gold standard of pharmacological treatment…The Efficacy and Safety of Subcutaneous Apomorphine in Patients with Parkinson’s Disease: A Meta-Analysis Randomized Controlled Trials
Objective: The objective of this study to evaluate the efficacy and safety of subcutaneous apomorphine for patients with Parkinson’s disease (PD). Background: Subcutaneous apomorphine has…Non motor fluctuations in Parkinson’s disease: Findings from a Tunisian cohort
Objective: To evaluate the frequency of non motor fluctuations (NMF) in Parkinson's disease (PD), their correlation with motor complications and their impact on the quality…
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