Freezing of Gait in Parkinson’s Disease: Risk Factors and Associated Nonmotor Symptoms
Objective: To clarify risk factors for, and clinical associations of, freezing of gait (FOG) in Parkinson's disease (PD). Background: FOG is a disabling and incompletely…Efficacy and safety of the 5-Hydroxytryptophan on Levodopa-Induced Motor Complications in Parkinson’s disease.
Objective: To evaluate the efficacy of the 5-Hydroxytryptophan (5-HTP) on levodopa-induced motor complications in patients with Parkinson's disease (PD). Background: Several studies have indicated that…Cholecalciferol (VD3) attenuated motor deficits and dyskinesia in Hemi-Parkinsonian mice: behavioural, biochemical & electrophysiological implications
Objective: The study investigated the impacts of VD3 on behavioural indices, dopamine metabolism, DA transport, BDNF, corticostriatal neural activities and the possible mechanism of action…Measurement properties of the MDS-NMS Non-motor Fluctuations Subscale
Objective: This study aims at describing the measurement properties of the Non-motor Fluctuations (NMFs) subscale of the Movement Disorders Society Non-Motor Rating Scale (MDS-NMS) according…Opicapone improves motor and non-motor wearing off symptoms in Parkinson’s disease: an observational real-world study
Objective: To assess the impact of opicapone - a third generation COMT Inhibitor - on motor and non-motor wearing off symptoms in patients suffering from…Demographic Influences on Wearing Off Symptoms in Parkinson’s Disease
Objective: To examine differences in wearing off symptoms in Parkinson’s Disease (PD) according to gender, age, and age at PD diagnosis. Background: Off symptoms in…Exploring the relationship between motor and non-motor fluctuations in Parkinson’s disease: patient’s perspective, clinician’ s assessment and objective measures from a wearable device
Objective: We aimed: 1) To evaluate the relationship between motor (MF) and non-motor (NMF) fluctuations in Parkinson’s disease measured with patient’s self-assessment, clinician’s evaluationand objective measurement using a wearable…Polyneuropathy in patients with continuous levodopa/carbidopa intestinal gel (LCIG) infusion
Objective: To assess frequency of polyneuropathy in patients with LCIG and the usefulness of routine nerve conduction studies follow-up Background: Continuous levodopa infusion is an…Do non-motor fluctuations temporarily match ON/OFF motor condition?
Objective: The aim of this study was to explore the relation between non-motor neuropsychological fluctuations, identified with the Neuropsychiatric Fluctuation Scale (NFS), and motor fluctuations…BouNDless: An active-controlled randomized, double-blind double-dummy study of continuous ND0612 infusion in patients with fluctuating Parkinson’s disease
Objective: Determine the efficacy, safety, and tolerability of continuous subcutaneous ND0612 infusion in comparison to oral Carbidopa/Levodopa (CD/LD) in patients with Parkinson’s disease (PD) experiencing…
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