MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Wearing-off fluctuations"

  • 2025 International Congress

    Evaluation of Local Field Potential-guided DBS-programming in a Parkinson’s disease outpatient clinic

    V. Zentsch, N. Warneke, I. Aymanns, D. Putzer, T. Huchtemann, T. Warnecke, I. Claus (Muenster, Germany)

    Objective: To evaluate potential use and applicability of local field potential-guided DBS-programming under real-life conditions in a Parkinson’s disease (PD) outpatient clinic. Background: Deep brain…
  • 2025 International Congress

    Computer Vision Quantification of Repeated Finger Tapping Demonstrates Aberrant Plasticity in Parkinson’s Disease

    D. Newbold, U. Kang (New York, USA)

    Objective: Test if symptoms of Parkinson's disease (PD) develop through aberrant plasticity. Background: Recent results in 6-hydroxydopamine-lesioned mice show that repeated performance of simple motor…
  • 2025 International Congress

    Opicapone for OFF Motor Fluctuations in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Trials

    A. Fornari Caprara, J. Pitton Rissardo (Camden, USA)

    Objective: To evaluate the efficacy of opicapone 50 mg in reducing OFF time and improving motor function in Parkinson’s disease (PD) patients with motor fluctuations.…
  • 2025 International Congress

    Safinamide as an Adjunct Therapy for Motor Symptoms and ON-Time Extension in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    A. Fornari Caprara, J. Pitton Rissardo (Camden, USA)

    Objective: To evaluate the efficacy of safinamide as an adjunct therapy in improving motor symptoms and extending ON-time in patients with Parkinson’s disease (PD). Background:…
  • 2025 International Congress

    Early Introduction of COMT Inhibitors at Low Levodopa Doses Improves Long-Term Motor Complications in Parkinson’s Disease: A sub-analysis of the REONPARK Study

    J. García-Caldentey, D. Vilas Roldán, L. López-Manzanares, H. Brigas, D. Martins, J. Reis, J. Blanco Ameijeiras, M. Rodríguez-de Miguel, I. Tegel Ayuela (Palma de Mallorca, Spain)

    Objective: This sub-analysis of the REONPARK study aims to identify predictive factors for the greater effectiveness of COMT inhibitors (COMTi) in alleviating motor complications in…
  • 2025 International Congress

    Dosage Optimization and Treatment Outcomes of Foslevodopa/Foscarbidopa Continuous Subcutaneous Infusion in Parkinson’s Disease: a single center study

    K. Kakuda, Y. Kimura, K. Ikenaka, H. Mochizuki (Suita, Japan)

    Objective: To optimize the dosage of foslevodopa/foscarbidopa continuous subcutaneous infusion (CSCI) therapy for Parkinson’s disease by identifying dosage differences between the continuation and discontinuation groups.…
  • 2025 International Congress

    COMT-Inhibitors Clinical Experience In Early Motor Fluctuations. Three Months Analysis Of REONPARK Study

    L. López-Manzanares, M. Cerdán Sánchez, T. Delgado Ballestero, B. Solano Vila, J. García-Caldentey, A. Rodríguez-Sanz, H. Brigas, D. Martins, J. Blanco Ameijeiras, M. Rodríguez-de Miguel (Madrid, Spain)

    Objective: The REONPARK study aims to evaluate COMT inhibitors (COMTi) effectiveness and tolerability in alleviating motor complications associated with L-dopa treatment in Parkinson’s disease (PD)…
  • 2025 International Congress

    COMT-Inhibitors Clinical Experience In Early Motor Fluctuations. Six Months Analysis Of REONPARK Study

    L. López-Manzanares, M. Cerdán Sánchez, B. Solano Vila, J. García-Caldentey, A. Rodríguez-Sanz, J. Olivares Romero, H. Brigas, D. Martins, J. Blanco Ameijeiras, M. Rodríguez-de Miguel (Madrid, Spain)

    Objective: The REONPARK study aims to evaluate COMT inhibitors (COMTi) effectiveness and tolerability in alleviating motor complications associated with L-dopa treatment in Parkinson’s disease (PD)…
  • 2025 International Congress

    Zonisamide for Motor Symptoms and OFF-Time Reduction in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    J. Pitton Rissardo, A. Fornari Caprara (Camden, USA)

    Objective: To evaluate the efficacy and safety of zonisamide as an adjunct therapy for improving motor function and reducing OFF-time in patients with Parkinson’s disease…
  • 2024 International Congress

    Real-world Programming and Sensing from Adaptive Deep Brain Stimulation for Parkinson’s Disease in Japan

    G. Oyama, K. Kimura, H. Kishima, N. Murase, Y. Tsuboi, T. Tsuboi, T. Takezaki, Y. Higuchi, T. Hashimoto, Y. Shimo, T. Brionne, I. Buffin, K. Hidaka, F. Coletti, R. Amit, N. Morelli, H. Mure, H. Oshima (Tokyo, Japan)

    Objective: To characterize programming configurations and local field potentials (LFP) control parameters in a multicenter, real-world cohort of patients receiving deep brain stimulation (DBS) for…
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