Diagnostic Spectrum in a Cohort of Atypical Atypical Parkinsonism
Objective: To retrospectively look at atypical Parkinsonism mimics in our cohort and reappraise the clinical features of these subset of patients Background: Atypical parkinsonism syndromes…18F-Florzolotau PET uncovers the Co-pathological Heterogeneity of Tau Protein in Dementia with Lewy Bodies
Objective: We attempted to reveal the topographical deposition patterns of tau proteins in the living brains of patients with DLB in vivo by virtue of…Sex Differences for Regional Lewy Body Pathology in Pathologically-Defined Lewy Body Dementia
Objective: To investigate sex differences for regional Lewy body (LB) pathology burden, and regional LB pathology association with clinical diagnosis across people with a high…Identification of Novel Blood Biomarkers among Data-Driven Parkinson’s Disease Clusters in Asian Populations
Objective: The aim of this study is to explore the correlation between emerging serum biomarkers and subtypes of Parkinson's disease (PD). Background: PD is a…Early Syndromes and Clinicopathologic Progression in Progressive Supranuclear Palsy
Objective: We aimed to characterize early clinical features of progressive supranuclear palsy (PSP) that might correlate with clinical course and neuropathologic findings. Background: Progressive supranuclear…Familial Multiple System Atrophy-Mimics: Importance of Comprehensive Evaluation
Objective: We present two patients initially diagnosed as familial MSA until one of the patients was proven to be metachromatic leukodystrophy (MLD). Background: Multiple system…Ethnic Diversity and Symptomatology in Parkinson’s Disease with a Focus on Falls and Vertical Gaze Palsy
Objective: The objective of this study was to explore atypical features in the clinical phenotype of people with Parkinson’s disease (PwP) enrolled in the East…New α-Synuclein Strain Biomarker in Parkinson’s Disease and Related Dementia
Objective: Biomarker development for Parkinson’s disease and related dementia. Background: α-Synuclein (α-syn) strains can serve as discriminators of Parkinson's disease (PD) from other α-synucleinopathies. However,…Impact of Prior Head Trauma on Parkinson’s Disease Experience
Objective: We aim to characterize the impact of prior head trauma on Parkinson’s disease (PD) related outcomes. Background: Previous head trauma is correlated with detrimental…Unveiling the Link: Insulin’s Novel Role in Modulating α-Synuclein Accumulation in Parkinson’s Disease
Objective: This study marks the inaugural attempt to investigate the direct effects of insulin on pathological α-synuclein accumulation induced by the addition of α-synuclein preformed…
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