Differentiating White-Matter Damage Patterns by Underlying Pathology in Corticobasal Syndrome
Objective: This study aims to describe the patterns of white-matter damage using diffusion tensor imaging (DTI) in individuals with Corticobasal Syndrome (CBS) and compare the…An Interesting Case of Oculo-Palatal-Pharyngeal Tremor
Objective: We present a case report of a 59 year old with a diagnosis of clinically possible progressive supranuclear palsy (PSP) and clinical finding of…White Matter Abnormalities in Progressive Supranuclear Palsy (PSP) vs. Parkinson’s Disease (PD): Evaluation with a Convolutional Neural Network (CNN)-Based Tool
Objective: This study aimed to compare white matter hyperintensity (WMH) burden between PSP and PD using a novel AI-based tool for more accurate WMH volume…Resolution Dependence of Machine Learning for Differential Diagnosis of Parkinsonian Eye Movements
Objective: To establish the extent to which high temporal resolution is required to differentiate between parkinsonian disease states from eye movements. Background: Previous studies have…Compensatory Dynamic Brain Network Mechanisms in Early Lewy Body Dementia: An rs-fMRI Study
Objective: To investigate compensatory dynamic brain network mechanisms in early Lewy body dementia (LBD), specifically mild cognitive impairment with Lewy bodies (MCI-LB), using resting-state functional…Novel Heterozygous Variant in DCTN1 Associated with Perry Syndrome
Objective: To identify novel mutations in DCTN1 associated with autosomal dominant Perry syndrome and investigate their potential pathogenic mechanisms. Background: Perry syndrome is a neurodegenerative…Retrospective analysis of MSA diagnosis in a neuroscience hospital
Objective: We evaluated the extent to which diagnoses of MSA align with the MDS criteria within a specialist neurology trust in the UK. We aimed…Assessing Disease Progression in MSA: Development of a Bayesian Progression Model
Objective: Develop a Bayesian progression model (BPM) for MSA that leverages individual-level data derived from long-term follow up and offers a clinically interpretable, slope-based primary…Clinical Deficits, Quality of Life and Caregiver Burden across PSP Phenotypes
Objective: To assess clinical deficits, quality of life and caregiver burden across progressive supranuclear palsy (PSP) phenotypes considering also other variables such as age, sex…Artificial Intelligence in the Early Detection of Parkinson’s Disease: Advances, Challenges, and Future Perspectives
Objective: This study reviews AI’s role in early PD detection, comparing AI-driven diagnostic methods with conventional clinical approaches in accuracy, reliability, and applicability. Background: Parkinson’s…
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