BDNF(V66M), EIF4G1(R1205H), VPS35(D620N) gene polymorphisms in South Indian PD Patients
Objective: To investigate the association of BDNF(V66M), EIF4G1(R1205H) and VPS35(D620N) polymorphisms in South Indian PD patients. Background: Parkinson’s disease (PD) is the most common form…Full sequencing and haplotype analysis reveals LRRK2 protective haplotype in REM sleep behavior disorder
Objective: To examine the role of LRRK2 mutations and variants in susceptibility for RBD. Background: Rapid eye movement (REM)-sleep behavior disorder (RBD) is, in most…Lysosphingolipids accumulation in macrophage model of Gaucher disease
Objective: The aim of this study was to investigate if GCase deficiency in macrophage model of GD lead to lysosphingolipids accumulation. Background: Mutations in the…Association analysis of miRNA-linked variants with Parkinson’s disease and multiple system atrophy in a large Chinese population
Objective: To explore the relationship between two miRNA-linked variants (SPPLB rs1128402 and PDXK rs2070535) and two neurodegenerative diseases (PD and MSA) in a large Chinese…Relationship between cyclooxygenase-2 gene polymorphisms and Parkinson’s disease susceptibility in Chinese Han population
Objective: To investigate relationship between the cyclooxygenase-2 (COX-2) gene promoter region (rs20417, rs689466, rs689465) and 3'untranslated region (rs5275) polymorphisms with Parkinson’s disease (PD) susceptibility in…Novel population-specific mutationsin PINK1 and Parkin genes from India
Objective: To look for novel and population-specific genes for PD in 50 Indian families with Parkinson's disease Background: Till date, 138 mutations in PINK1 and…Molecular-genetic nature of Parkinson’s disease in the East European cohort
Objective: Genetic testing of the Parkin gene in patients with Parkinson's Disease (PD) in the East European cohort from Belarus. Background: The diagnosis of Juvenile…Microarray analysis upon an synthetic α-synuclein induced model reveals some susceptibility genes in Parkinson’s disease
Objective: To uncover new disease-associated genes and their relevant mechanisms in the pathogenetic process of neurodegenerative disorders, we carried out a gene microarray analysis based…Genetic variations of SNCA and striatal dopaminergic dysfunction in patients with Parkinson’s disease
Objective: The aim of the present study was to investigate genetic variants in SNCA associated with accelerated deterioration in striatal dopaminergic activity. Background: Widespread a-synuclein…Variants in MCCC1/LAMP3 and DGKQ Identified Through GWAS are Not Associated with PD in a Malaysian Malay Cohort
Objective: To investigate the association between variants in MCCC1/LAMP3 (rs12637471, rs12493050, rs10513789) and DGKQ (rs11248060) with PD in a Malay cohort. Background: Previous genome-wide association…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.