Relationship between striatal dopamine depletion and various non-motor symptoms in non-demented patients with Parkinson’s disease: a pilot study
Objective: We aimed to investigate associations of striatal dopamine uptake and various non-motor symptoms in non-demented patients with Parkinson’s disease (PD). Background: Dopamine transporter (DAT)…Characteristics of spontaneous brain activity in left- and right-onset Parkinson’s disease patients
Objective: To explore the characteristics of spontaneous brain activity in left- and right-onset Parkinson’s disease (PD) patients Background: It is well-know that PD patients often…Disrupted Functional Brain Connectome in Parkinson’s Disease Patients with Freezing of Gait
Objective: To investigate topological organization of the functional brain connectome in Parkinson’s disease (PD) patients with freezing of gait (FOG). Background: The cumulative evidence of…Cerebellar Structural changes in Patients with Parkinson’s disease and Essential Tremor
Objective: To assess differences in cerebellar lobar volumes in Essential tremor and Parkinson’s disease patients and investigate the relation of lobar volumes with motor symptoms.…Is awake physiological confirmation necessary for DBS treatment of Parkinson’s disease today? A comparison of intraoperative imaging, physiology, and physiology imaging-guided DBS in the past decade
Objective: To comprehensively compare the use of IMG-DBS, PHY-DBS and COMB-DBS in treating PD. Background: Deep brain stimulation (DBS) is a well-established surgical therapy for…Metabolic network abnormalities in drug-naive Parkinson’s disease
Objective: The objective of this study is to identify and validate the metabolic PD-related pattern (PDRP) in de novo PD patients and to compare it…Structural and functional MRI brain alterations of Lewy body diseases
Objective: We aimed to identify structural and functional brain MRI features of most aggressive phenotypes comparing three clusters of patients with idiopathic and genetic Lewy…Differentiating the substantia nigra pars compacta and ventral tegmental area in early-stage Parkinson’s disease using quantitative susceptibility mapping
Objective: To assess iron levels in dopaminergic midbrain nuclei using quantitative susceptibility mapping for identification of biomarkers of PD. Background: The midbrain dopaminergic system plays…The Use of Diffusion Weighted Imaging to Detect Structural Biomarkers in Recently-Diagnosed Parkinson’s Disease Patients
Objective: To quantify biomarkers for recently-diagnosed PD patients in the midbrain and their dopaminergic connections to the striatum. Background: The development of improved PD treatments…Functional Biomarkers of Parkinson’s Disease: Changes in Brain-Wide Network Connectivity in Default Mode and Fronto-Parietal Control Networks
Objective: Parkinson’s disease (PD) is a neurological disorder with no reliable biomarkers. We aimed to investigate naturalistic paradigms as functional biomarkers that distinguish between PD…
