A Study to Evaluate the Efficacy of PRX002/RG7935 in Participants With Early Parkinson’s Disease (PASADENA) – Study Design
Objective: To evaluate the efficacy of the anti-alpha-synuclein monoclonal antibody PRX002/RG7935 in a proof-of-concept Phase 2 study in patients with early Parkinson’s disease (PD). Background:…Clinical effectiveness of a highly challenging balance training (HiBalance program) for Parkinson’s disease: A multi-center clinical effectiveness trial
Objective: To determine the effectiveness of the adapted HiBalance program on balance control and gait among people with mild-moderate PD when performed in multiple clinical…A multimodal motor skill balance training with rhythmical cues to improve and maintain balance control in Parkinson’s disease
Objective: To study the effectiveness of Multimodal Motor Skill Balance Training (MBT) with rhythmical auditory cues to improve balance control and reduce falls in PD.…Ambulosono – A Music Walking Program Improves Gait Disorders in Parkinson’s Disease
Objective: The aim of the study was to study the effect of Ambulosono - a music walking program on the walking ability of patients with…A Virtual Reality Exercise Program Improves the Balance Function and Quality of Life of Patients with Parkinson’s Disease
Objective: This study were designed to evaluate the effectiveness of a 12-week virtual reality exercise program involving the Nintendo Wii(Wii), in improving balance and quality…Outcomes of a Prospective, Multi-center International Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: The objective this report is to describe collected outcomes from a large scale registry of a Deep Brain Stimulation (DBS) system capable of Multiple…Effect of dual task as rehabilitation therapy in Parkinson’s disease in the UPDRS III
Objective: To determine the effect of the dual task used as Rehabilitation therapy in the UPDRS III of patients with Parkinson's disease. Background: Parkinson's disease…The efficacy of intensive inpatient rehabilitation treatment in Parkinson’s disease patients
Objective: We investigated the efficacy of intensive impatient rehabilitation treatment in Parkinson's disease patients Background: Rehabilitation treatments have beneficial effects in Parkinson’s disease (PD).We determined…Inhibition of HDAC4 attenuates rotenone-induced abnormal increase of α-synuclein levels and affects autophagic flux in human dopaminergic SH-SY5Y cells
Objective: To explore the effects of selective inhibition of HDAC4, on levels of α-syn and autophagy-related proteins in PD. To discuss the mechanism for the…Directional Deep Brain Stimulation: First experiences in centers across the globe
Objective: To evaluate how clinicians are implementing directional DBS technology in their routine care. Background: Directional DBS is a new technology, which increases the clinician’s…
