MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Investigating the clinical predictors of depression in Huntington’s disease: An Enroll-HD Database Study

    E. Furr Stimming, G. Colpo, N. Rocha, A. Teixeira (Houston, TX, USA)

    Objective: This study was designed to investigate clinical predictors of depression in subjects with HD. Background: Huntington’s disease (HD) is characterized by motor, cognitive and…
  • 2018 International Congress

    Comparing risperidone and olanzapine to tetrabenazine for the management of Huntington’s chorea

    J. Schultz, J. Kamholz, P. Nopoulos, A. Killoran (Iowa City, IA, USA)

    Objective: To compare the efficacy of risperidone and olanzapine to tetrabenazine (TBZ) for the management of Huntington’s chorea in Enroll-HD participants. Background: TBZ is provenly-effective…
  • 2018 International Congress

    The impact of bilingualism in brain structure and function in early and mild Huntington’s disease

    S. Martinez-Horta, A. Moreu, F. Sampedro, J. Perez-Perez, A. Horta-Barba, J. Pagonabarraga, J. Marin-Lahoz, H. Bejr-Kasem, J. Kulisevsky (Barcelona, Spain)

    Objective: To explore the impact of different levels of lifelong use of bilingualism on brain structure and metabolism in early and mid-stage Huntington’s disease (HD);…
  • 2018 International Congress

    Prevalence of Single Nucleotide Polymorphisms (SNPs) rs362307 or rs362331 in Patients with Huntington’s Disease

    S. Hung, D. Claassen, M. Edmondson, R. Reilmann, N. Svrzikapa, K. Longo, J. Goyal, M. Panzara (Cambridge, MA, USA)

    Objective: An observational research study is being conducted in patients with Huntington’s disease (HD) to determine the frequency with which the thymine (T) variant of…
  • 2018 International Congress

    Neurofilament light protein: An emerging clinical and translational biofluid biomarker for Huntington’s disease

    L. Byrne, F. Rodrigues, E. Johnson, S. Gregory, R. Soylu Kucharz, M. Björkqvist, A. Heslegrave, K. Blennow, A. Durr, B. Leavitt, R. Roos, S. Tabrizi, H. Zetterberg, D. Langbehn, R. Scahill, E. Wild (London, United Kingdom)

    Objective: To investigate whether neurofilament light protein (NfL) a potential prognostic marker of neurodegeneration with Huntington’s disease. Background: NfL, a component of the axonal cytoskeleton,…
  • 2018 International Congress

    Huntington disease like 2 in South Africa

    M. Khider, K. Naidu, J. Carr (Cape Town, South Africa)

    Objective: Background: Since the Huntingtin gene was identified in 1993, it has been recognized that a small proportion of patients with a clinical syndrome resembling…
  • 2018 International Congress

    Neuroprotective role of cinnamaldehyde against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington’s disease

    P. Kashyap, S. Gupta (Bihar, India)

    Objective: The present study examined the potential therapeutic effects of CA against 3-nitropropionic acid (3-NP)-induced oxidative stress in a rat model of HD and explored…
  • 2018 International Congress

    A Study on Combined Brain Positron Emission Tomography (PET) – Magnetic Resonance Imaging (MRI) Using Fluorodeoxyglucose (18FDG) (FDG-PET/MRI) in Premanifest Huntington’s Disease Gene-expansion Carriers

    M. Hellem, T. Vinther-Jensen, C. Hansen, E. Budtz-Jørgensen, L. Hjermind, I. Law, J. Nielsen (Copenhagen, Denmark)

    Objective: By a combined brain PET–MRI using FDG, we wished to simultaneously characterize the structural and metabolic brain changes in premanifest HD gene-expansion carriers. Background:…
  • 2018 International Congress

    Driving performance of Huntington’s disease gene carriers

    M. Jacobs, E. Hart, Y. Mejia Miranda, G.J. Groeneveld, J. van Gerven, R. Roos (Leiden, Netherlands)

    Objective: To investigate if differences in driving performance between Huntington's disease (HD) gene carriers and healthy individuals can be detected with a driving simulator. Furthermore,…
  • 2018 International Congress

    Malignant gliomas in patients with Huntington’s disease

    S. Chandra, G. Suarez-Cedeno, E. Stimming (Houston, TX, USA)

    Objective: Discuss the presentation of glioblastoma multiforme in patients with Huntington’s disease Background: Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by a trinucleotide…
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