Investigating the clinical predictors of depression in Huntington’s disease: An Enroll-HD Database Study
Objective: This study was designed to investigate clinical predictors of depression in subjects with HD. Background: Huntington’s disease (HD) is characterized by motor, cognitive and…Comparing risperidone and olanzapine to tetrabenazine for the management of Huntington’s chorea
Objective: To compare the efficacy of risperidone and olanzapine to tetrabenazine (TBZ) for the management of Huntington’s chorea in Enroll-HD participants. Background: TBZ is provenly-effective…The impact of bilingualism in brain structure and function in early and mild Huntington’s disease
Objective: To explore the impact of different levels of lifelong use of bilingualism on brain structure and metabolism in early and mid-stage Huntington’s disease (HD);…Prevalence of Single Nucleotide Polymorphisms (SNPs) rs362307 or rs362331 in Patients with Huntington’s Disease
Objective: An observational research study is being conducted in patients with Huntington’s disease (HD) to determine the frequency with which the thymine (T) variant of…Neurofilament light protein: An emerging clinical and translational biofluid biomarker for Huntington’s disease
Objective: To investigate whether neurofilament light protein (NfL) a potential prognostic marker of neurodegeneration with Huntington’s disease. Background: NfL, a component of the axonal cytoskeleton,…Huntington disease like 2 in South Africa
Objective: Background: Since the Huntingtin gene was identified in 1993, it has been recognized that a small proportion of patients with a clinical syndrome resembling…Neuroprotective role of cinnamaldehyde against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington’s disease
Objective: The present study examined the potential therapeutic effects of CA against 3-nitropropionic acid (3-NP)-induced oxidative stress in a rat model of HD and explored…A Study on Combined Brain Positron Emission Tomography (PET) – Magnetic Resonance Imaging (MRI) Using Fluorodeoxyglucose (18FDG) (FDG-PET/MRI) in Premanifest Huntington’s Disease Gene-expansion Carriers
Objective: By a combined brain PET–MRI using FDG, we wished to simultaneously characterize the structural and metabolic brain changes in premanifest HD gene-expansion carriers. Background:…Driving performance of Huntington’s disease gene carriers
Objective: To investigate if differences in driving performance between Huntington's disease (HD) gene carriers and healthy individuals can be detected with a driving simulator. Furthermore,…Malignant gliomas in patients with Huntington’s disease
Objective: Discuss the presentation of glioblastoma multiforme in patients with Huntington’s disease Background: Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by a trinucleotide…
