A Novel Dopaminergic Modulator (NDM-101) as an Adjunct to Levodopa: Enhancing Motor Control Without Worsening Dyskinesia in Parkinson’s Disease
Objective: To evaluate the efficacy and safety of NDM-101 as an adjunct to levodopa in reducing OFF-time, improving motor function, and maintaining quality of life…Repeated Scanning Ultrasound in an Alpha-synuclein Preformed Fibril model
Objective: To investigate the therapeutic potential of repeated scanning ultrasound (SUS)-mediated blood-brain barrier (BBB) opening in a mouse model of Parkinson’s disease (PD). Background: PD…Hashimoto Encephalopathy, A Choreiform Presentation
Objective: We report the case of a woman with chorea as lonely feature Background: Hashimoto encephalopathy is a rare autoimmune and vasculitis encephalopathy. The first…Traumatic DBS Implant exposure following head injury and its management – a case report.
Objective: To present management plan employed in treatment of a case of traumatic exposure of lead wires in a known case of Idiopathic Parkinson’s disease(PD)…A Case of SGCE Myoclonus-Dystonia diagnosed in a 70-Year-Old Male
Objective: N/A Background: SGCE myoclonus-dystonia (SGCE-M-D) is a movement disorder characterized by myoclonus and dystonia, primarily affecting the neck, trunk, and upper limbs. Patients may…Nutritional Parameter Changes in Parkinson’s Disease Patients Receiving Continuous Subcutaneous Infusion of Foslevodopa-Foscarbidopa
Objective: This study aims to assess changes in nutritional parameters in patients with Parkinson’s disease (PD) undergoing continuous subcutaneous infusion (CSCI) of foslevodopa-foscarbidopa. Background: Device-aided…Neuroprotective Effects of Co-Administered Hesperetin and Resveratrol Nanoparticles on Oxidative Stress and Neurobehavioral Deficits in Parkinson’s Disease
Objective: This study aimed to evaluate the therapeutic potential of solid lipid nanoparticles (SLNs) containing hesperetin (HE-SLN), resveratrol (RE-SLN), and their co-administration (HE-RE-SLN) in combating…Initial Evaluation of a Body-worn Bilateral Sensory Electrical Stimulation Cueing System in Reducing Freezing of Gait (FoG) in a Patient in the OFF and ON States
Objective: The objective was to carry out an in-clinic evaluation of a new body-worn bilateral Sensory Electrical Stimulation cueing system (Figure 1) designed to reduce…Deep Brain Stimulation in a Patient with Dystonia-Parkinsonism Secondary to a c.609G>A PLA2G6-Associated Neurodegeneration Variant
Objective: To describe a rare likely pathogenic variant of the PLA2G6 protein and its response to deep brain stimulation (DBS). Background: PLA2G6-associated neurodegeneration (PLAN) can…Improving Vocal Volume and Quality of Life for People with Parkinson’s Disease (PD) utilizing EMST and SPEAK OUT!® in the In-Patient Multimodal Intensive Neurorehabilitation And Care Setting.
Objective: To demonstrate the ability to improve vocal volume and improve perceived disability and quality of life in PD patients at the unstructured conversational level during…
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