Impact of Cognition on Social Engagement in Community-based Older Adults with Parkinsonism
Objective: To investigate how cognition and gait influence social engagement in parkinsonism. Background: Social engagement is vital to quality of life in parkinsonism, yet the…Dose Optimization of Foslevodopa/Foscarbidopa: Post Hoc Analysis of Study Completers
Objective: To describe dose optimization, efficacy, and safety of foslevodopa/foscarbidopa (LDp/CDp) in patients with advanced Parkinson’s disease (PwaPD) who completed a 52-week open-label study. Background:…Prospective observational study on the effects of physical exercise and lifestyle modifications in patients with Parkinson’s disease
Objective: This study aimed to assess the effectiveness of physical activity, which includes all movements that increase energy expenditure, in conjunction with exercise, characterized as…G-Can, the GBA1 Canada Initiative
Objective: G-Can, the GBA1 Canada Initiative, is an open-science platform which aims to advance GBA1 research and develop treatments for GBA1 mutation-related Parkinson's disease (PD).…Parkinson’s Disease Dogs to assist Gait Impairment: A Pilot study of Patient Experience and Outcomes
Objective: This pilot study was designed to evaluate Parkinson's disease assistance dogs as a novel non-pharmacological therapy for gait impairment in Parkinson's disease Background: Gait…A Novel Therapeutic Targeting the tPA-NMDAr Interaction for Parkinson’s Disease
Objective: Glunomab, a monoclonal antibody designed to inhibit the interaction between tissue plasminogen activator (tPA) and the N-methyl-D-aspartate receptor (NMDAr), has demonstrated therapeutic potential across…Impact of ND0612 on Levodopa-Induced Dyskinesia in Parkinson’s Disease: Post hoc Analyses From a Randomized, Active-Controlled Study
Objective: To evaluate dyskinesia-related outcomes between optimized subcutaneously administered levodopa/carbidopa (ND0612) + immediate-release levodopa/carbidopa (IR-LD/CD) vs optimized oral IR-LD/CD in patients with Parkinson’s disease (PD).…“Magic carpet for freezing of gait ” Evaluating a combination of patterned and pictographic visual cues.
Objective: To devise a portable skid free mat bearing a combination of patterned and pictographic visual cues for freezing of gait. Background: Freezing of gait…Incidence and Determinants of Nodule formation in continuous subcutaneous Foslevodopa/Foscarbidopa Infusion therapy.
Objective: This study aims to evaluate the incidence of subcutaneous (SC) nodules in Parkinson’s patients treated with continuous 24-hour SC infusion of foslevodopa/foscarbidopa (LDp/CDp) and…Longitudinal Remote Monitoring with Wearable Technology in Parkinson Disease: Initiation of A Dyskinesia Insight Network Observational Study
Objective: Evaluate the utility of wearable digital health technology for identifying and characterizing levodopa-induced dyskinesia in real-world settings. Background: Patients with Parkinson disease (PwP) frequently…
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