MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Floor square size predicts step count of 360° turns in PD patients with freezing

    U.M. Fietzek, L. Stuhlinger, A. Plate, A.O. Ceballos-Baumann, K. Bötzel (Munich, Germany)

    Objective: To determine the effect of floor square size on turning behavior in patients with PD. Background: Turning has been repeatedly shown to be the…
  • 2016 International Congress

    Differential expression of cerebral dopamine neurotrophic factor (CDNF) in the hippocampus and in the striatum of LRRK-2 mutant rat model of Parkinson’s disease

    J. Varghese, K. Terpstra, S. Chiu, R. Mishra, Y. Bureau (London, ON, Canada)

    Objective: The objective of our study was to characterize the behavioral phenotype of the transgenic LRRK-2 rat in the context of PD model and to…
  • 2016 International Congress

    Diffusion tensor imaging (DTI) within the primate caudate nucleus marks dopaminergic (DA) and serotonergic (5-HT) lesions

    S. Thobois, E. Météreau, M. Beaudoin-Gobert, S. Duperrier, L. Tremblay, V. Sgambato-Faure (Bron, France)

    Objective: To determine the best diffusion tensor imaging markers of dopaminergic and serotonergic lesions in the non-human primate. Background: DTI has received particular interest to…
  • 2016 International Congress

    Role of dopamine and GABA during subthalamic and pallidal deep brain stimulation: Evidence of dopamine release during subthalamic Deep Brain Stimulation

    A. Nakajima, Y. Shimo, T. Uka, N. Hattori (Tokyo, Japan)

    Objective: We recorded the single-unit activity of striatal cholinergic interneurons of healthy monkeys during high-frequency stimulation (HFS) of the subthalamic nucleus (STN) and globus pallidus…
  • 2016 International Congress

    Reach-to-grasp impairments of both hands in individuals with Parkinson’s disease

    S. Khacharoen, J. Tretriluxana, A. Pisarnpong, P. Chaiyawat (Nakhon Pathom, Thailand)

    Objective: To compare the reach-to-grasp (RTG) planning, kinematics and coordination of the less- (left) and more affected (right) hand in Individuals with Parkinson's disease (PD)…
  • 2016 International Congress

    Subthalamic nucleus activity during virtual reality provoked lower limb freezing in a patient with Parkinson’s disease and freezing of gait

    M.J. Georgiades, M. Gilat, J.M. Shine, J. McMaster, N. Mahant, S.J.G. Lewis (Sydney, Australia)

    Objective: Record subthalamic nucleus activity in a Parkinson's disease patient with gait freezing while they perform a virtual reality walking task during DBS surgery. Background:…
  • 2016 International Congress

    F1 crossbreds of C57BL/6 and CD-1 mice demonstrate resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced nigral neurodegeneration

    P.A. Alladi, D. Vidyadhara, H. Yarreiphang, T.R. Raju (Bengaluru, India)

    Objective: To establish the neural basis of varying susceptibility to MPTP in MPTP resistant CD-1 mice, susceptible C57BL/6 mice and their crossbreds; simulating the variable…
  • 2016 International Congress

    Involvement of peripheral immune system in the pathogenesis of Parkinson’s disease

    Y.X. Chao, S.C. Wong, K.J. Puan, J.J.Y. Tai, O. Rötzschke, B. Lee, M. Poidinger, E.K. Tan (Singapore, Singapore)

    Objective: To investigate the role of peripheral immune system in the pathogenesis of Parkinson's disease carrying LRRK2 risk variants. Background: Leucine-rich repeat kinase 2 (LRRK2)…
  • 2016 International Congress

    Piper longum L. alkaloids inhibit lipopolysaccharide-stimulated microglial activation and protect nigral dopaminergic neurons

    H. Yang, C. Duan (Beijing, People's Republic of China)

    Objective: The ethanol-extracted alkaloids from the dry seeds of Piper longum L. (PLL) (family Piperaceae) PLA contain numerous compounds. We evaluate the potential of PLA…
  • 2016 International Congress

    An exuberant cortical γb influences the unmasking and intensity of dyskinesia in 6-OHDA-treated freely-moving rats

    S. Galati, V. D'Angelo, A. Salvadè, A. Kaelin, A. Stefani (Lugano, Switzerland)

    Objective: To clarify the pathogenetic role of Beta band (βb) and Gamma band (γb) in 6-OHDA-treated freely-moving rats, by combining histochemical and electrophysiological investigations. Background:…
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