Dopaminergic denervation and focal motor progression in early Parkinson’s Disease: A 5-year longitudinal study
Objective: To evaluate the progression of posterior putamen dopaminergic denervation in relation to motor progression in the less affected and more affected side of the…Intraepidermal Nerve Fiber Density at Baseline Associates with One-year Clinical Disease Progression in Multiple System Atrophy
Objective: In a longitudinal manner explore possible diagnostic and prognostic properties of determining intraepidermal nerve fiber density (IENFD), by means of skin punch biopsy, in…Impact of Altered Cerebrovascular Reactivity on Midbrain Degeneration, Perfusion and White Matter
Objective: To evaluate whether altered cerebrovascular reactivity contributes to midbrain degeneration, perfusion abnormalities, or white matter disease in patients with Parkinson’s disease (PD). Background: Cerebrovascular…Perceptions of Diseases in Patients with Cervical Dystonia
Objective: To explore how perception of disease can impact stigma, mood, quality of life, and severity of symptoms in patients with cervical dystonia (CD). Background:…MRI Visible Perivascular Spaces are Associated with Disease Duration and Severity in Parkinson’s Disease
Objective: Determine whether enlarged perivascular spaces (ePVS) in Parkinson's disease (PD) is associated with worsening motor symptoms and disease progression. Background: PVS are fluid-filled channels…Explore cellular heterogeneities of orbitofrontal cortex in multiple system atrophy using spatial transcriptomics
Objective: To explore the spatial organization and cellular complexity of the orbitofrontal cortex (OFC) in multiple system atrophy (MSA) via spatial transcriptomic (SRT). Background: The…Visual Hallucinations and Pareidolias Across the Lewy Body Disease Spectrum
Objective: To systemically evaluate visual hallucinations and illusions in patients across the LBD spectrum and to discover the underlying neural mechanism behind these visual symptoms.…Association Between Cerebral Glucose Metabolism and Amyloid Deposition in Parkinson’s Disease
Objective: To investigate the potential association between cerebral amyloid (Aβ) deposition and regional brain metabolism in patients with Parkinson's disease (PD) Background: Although Parkinson's disease (PD)…Essential Tremor: The Relationship Between Hand Dominance and Tremor Severity by MVPA
Objective: The objective of this study was to analyze task-based functional Magnetic Resonance Imaging (task-fMRI) to investigate neural activity patterns in individuals diagnosed with Essential…Loneliness Relates to Gait Over Other Features of Parkinsonism
Objective: To assess the relationship between loneliness and facets of parkinsonism in community-based samples. Background: Loneliness increases the risk of mortality, dementia, depression, and motor…
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