The Impact of Statin Therapy on Motor and Non-Motor Symptoms in Parkinson’s Disease: A Meta-Analysis
Objective: To assess the effects of statin therapy on motor and non-motor symptoms in Parkinson’s disease (PD) through a meta-analysis of randomized controlled trials. Background:…Traditional Deep Brain Stimulation Programming versus Automated Image-Guided Algorithm in Patients with Parkinson’s Disease
Objective: To compare traditional initial deep brain stimulation (DBS) programming with artificial intelligence (AI)-assisted automated image-guided DBS programming algorithm. Background: DBS programming is a complex,…Cerebrospinal fluid measured α-synuclein is related to metabolite profile in the serum and CSF
Objective: Determine metabolites associated with cerebrospinal fluid (CSF) measured α-synuclein (α-syn) using untargeted metabolomics measured in the serum and CSF. Background: Several large studies have…Case Report of a Brazilian Family With New VUS for PLAN
Objective: The aim is to describe a Brazilian family with new VUS of PLA2G6 in two brothers with clinical symptoms of PLAN. Background: PLAN is…The Effectiveness of Rivastigmine in Parkinson’s Disease: Impact on Motor Symptoms, Gait, Cognitive Function, and Falls – A Systematic Review and Meta-Analysis of Double-Blind, Placebo-Controlled RCTs
Objective: To evaluate the efficacy of rivastigmine in patients with Parkinson’s disease (PD) by assessing its impact on motor symptoms, cognitive function, gait, falls, and…Detection of novel acoustic biomarkers among Parkinson’s disease patients via an explainable machine learning model
Objective: Our aim was to develop and compare machine learning (ML) algorithms for identification of Parkinson’s disease (PD) patients via acoustic analysis of vowel articulation…L-DOPA Induced Iron Accumulation in the Ventral Midbrain: The Roles of Sex and Iron Repletion
Objective: This study aims to investigate the impact of L-3,4-dihydroxyphenylalanine (L-DOPA) on ventral midbrain (VMB) iron levels under iron deficiency (ID) and repletion (IR) conditions…Cognitive Effects of Istradefylline in Parkinson’s Disease: A 26-Week Open-Label Pilot Study
Objective: The objective of this study was to collect preliminary evidence whether istradefylline may improve cognition in Parkinson’s disease (PD) patients with cognitive impairment. Background:…Results from the PRIME-UK Randomised Controlled Trial
Objective: To evaluate whether PRIME-Parkinson care increases the ability of people with parkinsonism (PwP) to achieve their personal goals, has a positive impact on health…Undescribed Variant of the THAP1 Gene Likely Pathogenic Associated with DYT6 – Case Report
Objective: To describe a case of dystonia DYT6 in which a variant of uncertain significance (VUS) in the THAP1 gene was found, which is likely…
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