Distinct roles of PARK2, PINK1, and LRRK2 in neuroinflammation: resistance and susceptibility in immune-mediated mouse models
Objective: To investigate the impact of PARK2, PINK1, and LRRK2 deficiency on neuroinflammation in aging, using immune-mediated mouse models. Background: Emerging evidence links mitophagy-related genes, including PARK2 (PARKIN), PINK1, and LRRK2, to immune…Differential Effect of Dopaminergic Treatment on Bradykinesia Features and Limb-kinetic Apraxia in Parkinson’s Disease
Objective: To investigate the differential effects of dopaminergic therapy on bradykinesia and limb-kinetic apraxia in PD patients using kinematic analysis. Additionally, transcranial magnetic stimulation (TMS)…Bassoon (BSN) Gene Mutations: A Missing Link in Gait and Balance Dysfunction Across Parkinsonian Disorders?
Objective: To elucidate the clinical significance of mutations in the Bassoon (BSN) gene in early-onset Parkinson’s disease (PD). Background: PD involves complex motor deficits beyond…Frequency of Falls in the Parkinson’s Progression Markers Initiative
Objective: To determine the faller rate across years since diagnosis and neuronal α-synuclein disease integrated staging system (NSD-ISS) stages in the Parkinson's Progression Markers Initiative…The Impact of Socioeconomic Status on Functionality in people with Parkinson’s Disease
Objective: To investigate the impact of socioeconomic status (SES) on functionality in people with Parkinson's disease (PD) using the World Health Organization Disability Assessment Schedule…The Role of Autophagy Lysosomal and Ubiquitin Proteasomal System in the Pathophysiology of Parkinson’s disease.
Objective: The research how to better understand the molecular mechanism initiating the etiology of Parkinson's disease in order to appropriate the precise diagnosis and therapeutic…Prevalence of Central Pain in Parkinson’s Disease: A Systematic Review and Meta-analysis
Objective: In this systematic review and meta-analysis, we aimed to evaluate the prevalence of central pain and how this symptom may affect the patient's quality…Predicting the Cognitive-Psychiatric Phenotype of Parkinson’s Disease
Objective: Predict PD patient’s clinical scores from brain activity. Inform on which assessments capture true changes in cortical dynamics caused by PD and explain those…Establishing a Timeline of Non-Motor and Motor Symptoms Progression in Parkinson’s Disease Using a Sub-Chronic MPTP Mouse Model
Objective: Parkinson’s disease (PD) mouse model using 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) was explored for pathological mechanisms driving non-motor symptoms (NMS). Aim was to map the behavioural changes…Neurodegeneration Biomarkers: Correlation between Hippocampal Volume and Cognitive Performance by MoCA Test in Parkinson’s Disease
Objective: This study aims to examine the relationship between hippocampal volume, assessed through magnetic resonance imaging (MRI), and MoCA test scores in patients diagnosed with…
- « Previous Page
- 1
- …
- 170
- 171
- 172
- 173
- 174
- …
- 1734
- Next Page »