Sensor-based motor state detection in Parkinson’s disease to approach personalized therapy delivery
Objective: As primary objective, we acquire a data pool of medically-treated PD patients with motor fluctuations to determine the sensitivity and specificity of algorithms capable…Randomized controlled trial protocol: Balance training with rhythmical cues to improve and maintain balance control in Parkinson’s disease
Objective: Is to evaluate the effects of balance training with rhythmical(BRT) which is a motor program to improve balance associated with rhythmical auditory cues (RACs).…Utilizing remote blood pressure monitoring in a phase III clinical drug trial for Parkinson’s disease
Objective: To determine the feasibility and value of remote blood pressure (BP) monitoring during a clinical trial of isradipine (a dihydropyridine calcium channel antagonist) in…Therapeutic protocol for Parkinson’s patient with freezing based on action observation plus sonification: Preliminary results
Objective: To evaluate the effects of a novel experimental protocol to treat patients with Parkinson's disease (PwP) and freezing of gait (FoG), using functional, and…The effects of intensive speech treatment on intelligibility in Spanish dysarthria secondary to Parkinson’s disease
Objective: To examine the effects of intensive speech treatment (LSVT-LOUD; Ramig et al., 2001) on intelligibility at conversational level in Spanish dysarthria secondary to Parkinson's…STEADY-PD III. A phase 3 study of isradipine as a disease modifying agent in patients with early Parkinson’s disease. Baseline characteristics of the enrolled cohort
Objective: To evaluate the efficacy of isradipine 10 mg daily on PD disability. Background: Isradipine, a dihydropyridine calcium channel antagonist with excellent penetration of the…A crossover study of pretarsal and preseptal injections of botulinum toxin type A (BTX-A) in the treatment of hemifacial spasm and blepharospasm
Objective: To compare the efficacy, patient satisfaction, and side effects between pretarsal and preseptal injection sites on BTX-A treatment in abnormal orbicularis oculi contraction in…Effect of outside influences on the therapeutic benefits of botulinum toxin injections
Objective: The purpose of this project is to determine if outside influences or stressors have an effect on the therapeutic benefit of botulinum toxin injections…Copper chelation efficacy of alginate/chitosan based D-penicillamine nanoparticles in rat model of non-Wilsonian brain copper toxicosis
Objective: To evaluate the copper (Cu) chelation efficacy of orally administered D-penicillamine loaded nanoparticles to that of conventional D-penicillamine therapy for 90 days in Wistar…Classification and recommendation of nonpharmacological therapies for Parkinson’s disease
Objective: A multidisciplinary specialized treatment including physiotherapy, speech and language therapy, occupational therapy (OT) associated to the ideal pharmacological treatment and surgical is recommended to…