Free water imaging of the cholinergic forebrain in body vs. brain-first Parkinson’s disease subtypes
Objective: To investigate the relationship between basal forebrain (BF) neurodegeneration and cholinergic system in body vs brain-first Parkinson’s disease (PD) subtypes. Background: Free water imaging…Representation of movement repertoire in subthalamic neural circuits using a markerless 3D behavioral tracking system.
Objective: This study aimed to investigate the spatiotemporal encoding of neurons in the subthalamic nucleus using a mouse model. Background: The subthalamic nucleus is a…Subacute parkinsonism associated with Zic4 antibodies: a case report
Objective: Describe a case of subacute parkinsonism associated with isolated Zic4 antibodies. Background: Movement disorders are a common feature in autoimmune encephalitis and its presentation…Loneliness, Self-Efficacy, and Resilience: Neglected Modifiable Contributors to Parkinson’s Disease Symptom Severity and Quality of Life
Objective: To evaluate the degree to which modifiable psychosocial (PS) variables including loneliness, self-efficacy (SE) and resilience explain the variance observed in Parkinson’s disease (PD)…Implementation and effects of telehealth exercise therapy on satisfaction and Mobility In persons with Parkinson’s.
Objective: To improve PD care and motor performance using telehealth exercise therapy in individuals with PD. Background: Parkinson’s disease (PD) is a chronic disease with…Association between type 2 diabetes mellitus with parkinson’s disease and the increase of the severity of depression and anxiety in a mexican population
Objective: To compare the severity of depression and anxiety in PwP between those with T2D and those without T2D. Background: Parkinson's disease (PD) is the…Impulse control disorder related to dopaminergic therapy in progressive supranuclear palsy
Objective: To report a patient with progressive supranuclear palsy (PSP) in whom an impulse control disorder (ICD) was triggered by a dopaminergic therapy. Background: ICDs…Clinical and radiological characteristics of a cohort of seventy-one Multiple System Atrophy patients
Objective: This study aimed to review the characteristics of large cohort of MSA patients diagnosis in our center, confirming previous clinical and imaging data from…Development of potent, orally bioavailable, and highly selective LRRK2 PROTAC® degrader molecules as potential disease modifying therapeutics for Parkinson’s disease
Objective: Report on the pharmacological characteristics of small molecule PROteolysis TArgeting Chimera (PROTAC) molecules designed to induce degradation of leucine rich repeat kinase 2 (LRRK2)…Phenotypic presentation of essential tremor patients with Rapid eye movement disorder
Objective: To describe the prevalence of rapid eye movement disorder (RBD) among essential tremor (ET) patients and its correlates in terms of associated motor and…
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