MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2023 International Congress

    From the Healthy Brain Ageing – HeBA – Cohort: Motivation for participating in the first online phase of HeBA

    P. Mahlknecht, T. Marques, C. Vega Moreno, C. Horlings, A. Garrido, S. Schade, C. Gomes, S. Ghosh, K. Rege, R. Rawal, C. Pauly, D. Mcintyre, K. Seppi, C. Trenkwalder, E. Tolosa, W. Poewe, V. Satagopam, R. Krueger, B. Mollenhauer, M. Marti (Innsbruck, Austria)

    Objective: We aim to understand the motivation of participants to join the first online-phase of the European multicenter Healthy Brain Ageing (HeBA; see Abstract 0748_1125_001612)…
  • 2023 International Congress

    The prevalence and characteristics of REM sleep behavior disorder in progressive supranuclear palsy patients.

    APH. Phoumindr, JSR. Srignean, RBH. Bhidayasiri (Bangkok, Thailand)

    Objective: To describe the prevalence and characteristics of RBD in patients diagnosed with PSP and to demonstrate the association with each PSP subtype. Background: Rapid…
  • 2023 International Congress

    Falls in Mild Cognitive Impairment with Lewy bodies (MCI-LB).

    E. Lirani Silva, S. Waite, C. Hamilton, P. Donaghy, J. O'Brien, J. Taylor, J. Lloyd, L. Allan, M. Firbank, A. Thomas, A. Yarnall (Newcastle, United Kingdom)

    Objective: to identify clinical, physical activity and mobility measures that differentiate patients with mild cognitive impairment with Lewy bodies (MCI-LB) fallers and non-fallers from cognitively…
  • 2023 International Congress

    Distinct deep grey matter iron accumulation in tremoric syndromes; an apparent quantitative susceptibility mapping mangetic resonance study

    A. Martín-Bastida, I. Aviles-Olmos, A. Gorospe-Osinalde, V. Suarez-Vega, P. Dominguez-Echavarri, R. García-Eulate, C. Sánchez-Catasús, MC. Rodríguez-Oroz (Pamplona, Spain)

    Objective: To investigate regional iron accumulation in patients with essential tremor (ET) and Parkinson´s disease (PD) and its clinical associations with apparent susceptibility-weighted imaging (SWI)…
  • 2023 International Congress

    Inhibition of LRRK2 kinase activity promotes glucocerebrosidase transport to the lysosomes in primary monocyte-derived macrophages from patients with GBA-associated Parkinson’s disease

    K. Basharova, A. Bezrukova, A. Izyumchenko, G. Baydakova, I. Miliukhina, E. Zakharova, S. Pchelina, T. Usenko (Gatchina, Russian Federation)

    Objective: The aim was to evaluate the effectiveness of leucine-rich repeat kinase 2 (LRRK2) kinase activity inhibition in restoring transport of the enzyme glucocerebrosidase (GCase),…
  • 2023 International Congress

    Incidence and Predictors of Axial Postural Abnormalities in Parkinson disease: data from the PPMI cohort

    CA. Artusi, C. Campisi, C. Ledda, K. Tsukita, D. Rinaldi, L. Lopiano, M. Fabbri (Torino, Italy)

    Objective: We aim to evaluate the incidence of axial postural abnormalities in patients with Parkinson’s disease (PD) and analyze their demographic and clinical predictors. Background:…
  • 2023 International Congress

    Anle138b-P1-02: A randomised, double-blinded, placebo-controlled phase 1b study to investigate safety, tolerability, pharmacokinetics and pharmacodynamics of the oligomer modulator anle138b in Parkinson´s disease

    J. Levin, N. Singh, S. Melbourne, A. Morgan, C. Carroll, U. Fietzek, S. Ryazanov, A. Leonov, CH. Griesinger, F. Schmidt, D. Weckbecker, K. Prager, T. Matthias, A. Giese (Wendelsheim, Germany)

    Objective: To present first-in-patient data of the oligomer modulator anle138b (TEV-56286, emrusolmin) in patients with Parkinson’s disease (PD). Background: Synucleinopathies such as PD and Multiple…
  • 2023 International Congress

    Emergent alpha-beta oscillations are accompanied with worsening motor symptoms in Parkinson’s disease

    E. Belova, U. Semenova, A. Gamaleya, A. Tomskiy, A. Sedov (Moscow, Russian Federation)

    Objective: The aim of the study was to imply observer-independent approach to search for the ranges of stable oscillations in broad alpha-beta range inside the…
  • 2023 International Congress

    Results from IRL790C005 – A Randomized, Double-Blind, Placebo-Controlled Phase IIb Study Evaluating the Efficacy of Mesdopetam on Daily On-Time without Troublesome Dyskinesia in Patients with Parkinson’s Disease

    A. Antonini, S. Waters, C. Sonesson, J. Landström, N. Waters, J. Tedroff (Padova, Italy)

    Objective: The objective of the Phase 2b-trial was to investigate efficacy and safety of three doses of Mesdopetam as adjunct treatment in patients with PD…
  • 2023 International Congress

    Characteristics of Huntington disease in a north Indian cohort

    D. Radhakrishnan, J. George, M. Faruq, R. Rajan, K. Kanojia, E. Arunmozhimaran, A. Das, A. Agarwal, A. Pandit, A. Srivastava (New Delhi, India)

    Objective: To describe the clinical and radiological profile of genetically confirmed Huntington’s disease (HD) patients from a single centre movement disorder (MD) clinic in Northern…
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