Olfactory neurons’ Substance P is highly expressed in Parkinson’s disease reflecting gastrointestinal dysfunction
Objective: To elucidate the role of Substance P in PD through molecular characterization of patients’ olfactory neurons. Background: Substance P is a neuropeptide largely expressed…Is a Parkinson’s Sialorrhoea service effective?
Objective: Evaluate the efficacy and tolerance of Botulinum Toxin A (BoNT A) in managing sialorrhoea in People with Parkinsons (PwP)Assess impact on quality of life…Utility of quantitative EEG during sleep as a potential biomarker of Lewy body disease progression
Objective: Objective: To assess whether progression from isolated REM sleep behaviour disorder (iRBD), established Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB) are accompanied…Sexual health and sleep quality in women living with Parkinson’s disease: are we neglecting that?
Objective: To investigate the relationship between sexual health and sleep quality in PD. Background: Sexual dysfunction (SD) is a common yet under-reported, non-motor symptom (NMS)…Transcranical Pulse Stimulation in Parkinson’s rest tremor: a pilot study.
Objective: The goal of this paper is to explore a possible effect of TPS on the PD rest tremor circuit, stimulating the motor cortex (M1)…Subjective cognitive complaints in participants of the Healthy Brain Ageing (HeBA) study
Objective: To investigate the prevalence of subjective cognitive complaints (SCC) from Healthy Brain Ageing Study (HeBA) participants in Luxembourg, and explore risk factors prevalence which…The Roche ‘End-to-End Matrix’ for Patient-Centric Drug Discovery and Development – Focus on Parkinson’s disease
Objective: To develop an ‘End-to-End Matrix’ for Patient-Centric Drug Discovery and Development to increase the probability of success of clinical trials in Parkinson’s disease. Background:…modulation of sodium potassium ATPase activity by norepinepherine and serotonin to find an effective cure of parkinson’s disease by introducing the novel concept of insilico drug repurposing
Objective: Parkinson's disease can cause neuropsychiatric disturbances which can range from mild to severe. This includes disorders of speech, cognition, mood, behaviour, and thought. In addition to…Cardiovascular autonomic function in GBA-associated Parkinson’s disease: a cross-sectional study
Objective: To objectively assess cardiovascular autonomic function in patients with Parkinson’s disease (PD) carrying pathogenic variants of beta-glucocerebrosidase gene (GBA-PD) and compare to non-mutated PD…DaT-Scans Have Limited Utility in Predicting Treatment Response to Ventriculoperitoneal Shunts in Normal Pressure Hydrocephalus
Objective: To determine usefulness of DaT-SPECT imaging in the management of normal pressure hydrocephalus (NPH). Background: Dopamine transporter single-photon emission computed tomography (DaT-SPECT) imaging is…
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