Reductions in OFF time with ND0612 for patients with Parkinson’s disease experiencing motor fluctuations: Responder-analysis from an open-label Phase 2 study
Objective: Evaluate the efficacy of subcutaneous levodopa/carbidopa infusion with investigational ND0612 in reducing OFF time in people with Parkinson’s disease (PwP) experiencing motor fluctuations. Background:…Cognitive profile of essential tremor patients: Beyond the cerebellar cognitive affective syndrome
Objective: To describe the cognitive profile of essential tremor (ET) patients and gain insight into its pathophysiological process. Background: Nowadays, ET is considered as a…Botulinum neurotoxin in FXTAS-related tremor: a “successful” case report
Objective: We report the case of a man affected by FXTAS, presenting with disabling tremor who experienced a significant and long-lasting benefit from botulinum neurotoxin…Preliminary evidence for evolution of myoinositol and N-acteylaspartate as biomarkers of disease severity in early-stage multiple system atrophy
Objective: To quantify the longitudinal evolution of metabolic indicators of gliosis and neuronal integrity in patients with multiple system atrophy (MSA) over one year. Background:…A role of transcranial sonography in evaluating patients with dystonia and tremor
Objective: The objective of this study was to assess changes in transcranial sonography (TCS) in patients with focal dystonia (FD) with or without tremor and…Subthalamic Nucleus Deep Brain Stimulation in GBA-associated Parkinson Disease: Cognitive and motor follow-up of two clinical cases
Objective: To report the long-term motor and cognitive outcome of two patients with GBA-associated Parkinson’s disease (PD) who underwent STN-DBS surgery. Background: Recent studies suggest…Impact of the COVID-19 pandemic in the long-term efficacy of botulinum toxin treatment
Objective: To analyse the impact of the COVID-19 pandemic in the long-term efficacy of treatment with botulinum toxin (BoT). Background: The COVID-19 pandemic brought new…Generalized chorea, cerebellar ataxia and spastic tetraparesis with a genetic mutation in FAT2 gene – coincidence or a new SCA45 phenotype?
Objective: To present what might be a new phenotype of spinocerebellar ataxia type 45. Background: Spinocerebellar ataxias (SCAs) are a heterogeneous group of autosomal dominant,…Gender-specific differences of gait in parkinsonian syndromes
Objective: The aim of this study was to further assess gender-specific gait and balance differences related to fall frequency in APD and IPD patients. Background:…First case of sporadic ATP6AP2 Mutation reported in Asia in a Parkinson’s Disease patient
Objective: Genetic analysis of Parkinson's Disease (PD) with features of spasticity by Whole Exome Sequencing (WES) and use of its result for treatment modification to…
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