MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2023 International Congress

    Long-term outcomes of deep brain stimulation for VPS16-related dystonia: A multi-center international study

    T. Svorenova, LM. Romito, E. Mulroy, L. Cif, E. Moro, KE. Zeuner, S. Zittel, JN. Petry-Schmelzer, M. Ostrozovicova, V. Han, V. Magocova, K. Knorovsky, A. Kollova, B. Garavaglia, N. Golfrè-Andreasi, C. Reale, A. Mazzoni, A. Kaymak, G. Zorzi, R. Eleopra, V. Levi, T. Foltynie, P. Limousin, H. Akram, L. Zrinzo, F. Magrinelli, D. Murphy, H. Houlden, MA. Kurian, C. Baiata, S. Paschen, K. Lohmann, J. Volkmann, W. Hamel, MT. Barbe, R. Jech, P. Havrankova, J. Winkelmann, M. Zech, M. Skorvanek (Košice, Slovakia)

    Objective: To evaluate long-term effects of DBS in an international cohort of people with VPS16-related dystonia. Background: Variants in VPS16 gene have recently been related…
  • 2023 International Congress

    Digital gait and turning impairments (quality but not quantity) during daily life are more severe in retrospective fallers compared to non-fallers with Parkinson’s disease

    V. Shah, C. Silva-Batista, P. Burgos, A. Ragothaman, P. Carlson-Kuhta, K. Sowalsky, F. Horak, M. Mancini (Porltand, USA)

    Objective: To investigate which specific digital gait and turning measures, obtained with body-worn sensors, best differentiate fallers from non-fallers with PD during daily life. Background:…
  • 2023 International Congress

    Continuous subcutaneous levodopa/carbidopa infusion with ND0612 for Parkinson’s disease: Three-year data from the open-label BeyoND study

    W. Poewe, A. Ellenbogen, F. Stocchi, L. Adar, L. Salin, R. Case, T. Yardeni, N. Giladi (Innsbruck, Austria)

    Objective: To evaluate three-year outcomes from the ND0612 BeyoND study. Background: Investigational ND0612 is in development as a 24-hour continuous, subcutaneous infusion of liquid levodopa/carbidopa…
  • 2023 International Congress

    The neuroprotective miRNA family hsa-miR-451 has a distinctive pattern of downregulation in neurodegenerative diseases.

    R. Singh, V. Swarup, I. Ahmad, V. Anand, I. Singh, M. Faruq, A. Srivastava (New Delhi, India)

    Objective: 1.Identification of microRNAs from whole blood PBMCs of SCA2 patients by using NGS.    2.To check the exclusivity of miRNAs in SCA2, SCA1,SCA3,SCA12,HD,ALS,PD and MSA-C…
  • 2023 International Congress

    Informing people with Parkinson’s disease of their gene variant status: PD GENEration, a North American observational and registry study

    L. Cook, J. Verbrugge, T. Schwantes-An, T. Foroud, A. Hall, K. Marder, I. Mata, N. Mencacci, M. Nance, M. Schwarzschild, T. Simuni, A-M. Wills, S. Rao, K. Ghosh Galvelis, A. Naito, J. Beck, R. Alcalay (Indianapolis, USA)

    Objective: To describe genetic testing results of major genes for Parkinson’s disease (PD) in a North American cohort as part of PD GENEration Background: Although…
  • 2023 International Congress

    Motor complications in Parkinson’s disease

    S. Gandhi, T. Zerenner, A. Nodehi, M. Lawton, K. Grosset, V. Marshall, F. Al-Hajraf, Y. Ben-Shlomo, M. Hu, D. Grosset (Glasgow, United Kingdom)

    Objective: To determine the presence, severity, functional impact and predisposing factors of motor complications. Background: Motor complications are well recognized in Parkinson’s disease (PD), but…
  • 2023 International Congress

    SAFE-DBS – A monocentric, randomised, blind evaluation of safinamide in the perioperative period in Parkinsonian patients with deep brain stimulation

    E. Gülke, M. Höfs, H. Pinnschmidt, A. Gulberti, C. Moll, U. Hidding, C. Buhmann, M. Heise, W. Hamel, M. Pötter-Nerger (Hamburg, Germany)

    Objective: This monocentric, randomised, blind study is designed to evaluate the effect of safinamide on motor and neuropsychiatric symptoms in the 3 month perioperative period…
  • 2023 International Congress

    Understanding patient perceptions of advanced Parkinson’s disease (aPD) treatments

    J. Domingos, R. Pahwa, A. Antonini, I. Malaty, S. Lindvall, F. de Renzis, C. Yan, K. Pantiri, N. Touba, E. Evans, A. Alobaidi, A. Shewale, M. Shah, P. Kukreja, J. Zamudio, K. Chaudhuri (Orpington Kent, United Kingdom)

    Objective: To explore patients’ perceptions of treatment options for aPD and treatment decision considerations. Background: As PD advances, some people with Parkinson’s (PwP) on oral…
  • 2023 International Congress

    Early-onset cortico-basal degeneration (CBD) due to a c.2092G>A MAPT mutation

    M. Mata Alvarez-Santullano, L. Lopez-Manzanares, J. Lopez-Lozano, N. Villares, C. Magdaleno, C. Dela Torre (Madrid, Spain)

    Objective: To describe a patient with early-onset atypical parkinsonism that evolved to a classic CBD without dementia, associated to a c.2092G>A MAPT mutation Background: Although…
  • 2023 International Congress

    Electronic Development of the MDS-UPDRS and MDS-NMS: Process and User Feedback

    R. Fuller, M. Monje, A. Sanchez Ferro, T. Mestre, L. Chahine, K. Dujardin, C. Fitzer-Attas, S. Groppa, S. Perez-Lloret, T. Turner, J. Youn, P. Martinez-Martin, G. Stebbins (Princeton, USA)

    Objective: To describe the processes for development and obtaining user feedback of the electronic versions of the MDS Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) and…
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