Baseline and Longitudinal NSD-ISS Staging of the PPMI Cohort
Objective: To apply biological definition and Neuronal α-Synuclein Disease Integrated Staging System (NSD-ISS) to the PPMI baseline and longitudinal dataset. Background: The NSD-ISS Working Group…Accuracy of Clinical features for Substantia Nigra Hypopigmentation and Cortical Lewy Body Presence in the Oldest-Old: The 90+ Study
Objective: To improve clinical diagnostic accuracy of Lewy Body Dementia (LBD), we assessed if frontal release signs are a useful screening tool for cortical Lewy…Association between Antiepileptic Drugs and Parkinson’s Disease: A Strong or Weak Link?
Objective: To perform a meta-analysis to show the association between different Antiepileptic Drugs(AEDs) and Parkinson’s disease(PD). Background: PD is a neurodegenerative disorder affecting 1-2% of…Driving assessment in older patients with Parkinson’s in United Kingdom.
Objective: To review existing pathway for driving assessment in older Parkinson’s patients in Royal Berkshire Hospital, Reading, UK. Background: Parkinson’s leads to motor, cognitive and…Development and Validation of a Clinical Scale for Distinguishing Multiple System Atrophy from 4-Repeat Tauopathies
Objective: We aimed to develop a clinical scale that distinguishes between Multiple System Atrophy (MSA) and 4-repeat tauopathies (4RT: CBD, PSP) using a standardized neurological…Parkinsonism due to Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) Responsive to Carbidopa/Levodopa
Objective: To describe a case of Parkinsonism due to ALSP which is responsive to carbidopa/levodopa Background: Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)…CANVAS: think to assess cognition!
Objective: To determine the frequency and severity of cognitive impairment in RFC1-positive patients and comprehensively describe the pattern of cognitive disorders. Background: Cerebellar ataxia, neuropathy,…PKG-Ethnicity project: An initial analysis of ethnical differences in Parkinson’s KinetoGraph (PKG) results between white and non-white ethnic groups
Objective: Using the Parkinson’s KinetiGraph (PKG) reports of PwP to determine if scores vary according to ethnicity, classed as white or non-white PwP (Black, Asian,…24-Hour Ambulatory Blood Pressure Monitoring and Dipping Patterns in Parkinson’s Disease and Multiple System Atrophy
Objective: To depict 24-hour blood pressure profile, especially dipping patterns, in individuals diagnosed with Parkinson’s Disease (PD) and Multiple System Atrophy (MSA). Background: Both PD…SARS-CoV-2 induced neurodegeneration in oxidative stress and genetic models of Parkinson’s Disease
Objective: Given similarities in systemic responses after infection with SARS-CoV-2 to those reported after the 1918 pandemic, we investigated whether SARS-CoV-2 could elicit a similar…
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