Utilizing the 15-item modification of the PSPRS rating scale (mPSPRS-15) as the primary endpoint for future clinical trials in progressive supranuclear palsy
Objective: To compare the properties of PSPRS-28, mPSPRS-15, and the rPSPRS-10 and assess their utility as a primary endpoint in PSP trials. Background: Progressive supranuclear…The Impact of Myofascial Release using Dry Needling on Gait in Parkinson’s Disease: A Pilot Study
Objective: The aim of this study was to analyze the length of the step during one cycle heel-to-heel and the time wasted to complete this…The Phenotypic Spectrum of ATP1A3-Related Disorders: A Brazilian Cohort
Objective: To describe a case series of patients with ATP1A3 variants, analyzing their phenotypic presentation and genetic characteristics in Brazil. Background: ATP1A3-related disorders exhibit a complex…Imbalance and falls in individuals with Hereditary Spastic Paraplegia
Objective: The aim of this systematic review is to assess imbalance and falls in patients with HSP through a systematic and comprehensive evaluation of the…“Parkinson Positivos”: A Collaborative Effort to Educate and Empower the Spanish-speaking community.
Objective: To create a culturally sensitive educational resource that (1) centers the voices of the Spanish-speaking community, (2) dispels misconceptions and breaks down barriers to…The Efficacy of Neuromodulation for Motor Recovery in Children with Hemiparesis Due to Perinatal Stroke: A Systematic Review and Meta-Analysis.
Objective: To assess the effectiveness of neurostimulation in enhancing motor function in children with perinatal stroke and hemiparetic cerebral palsy. Background: Neuromodulation techniques, including repetitive…Identification of Cerebrotendinous Xanthomatosis in Patients with Neurodegenerative Disorders from the Cincinnati Cohort Biomarker Program
Objective: To develop an algorithm for identifying patients with cerebrotendinous xanthomatosis (CTX) in a cohort of individuals with neurodegenerative disorders. Background: CTX is a rare…Archimedes spiral based non-linear regression machine learning model for predicting tremor’s severity
Objective: To predict tremor severity using the Archimedes spiral drawing, a commonly used item in tremor assessment scales. Background: The Archimedes spiral is widely used…Multimodal and Agentic Simulated AI Patients for Bridging the gap in Parkinson Disease Education
Objective: To develop an AI training platform in PD counseling that utilizes real-time NLP processing, multimodal inputs/outputs, and adaptive reinforcement learning supported by immediate feedback…Atypical Parkinsonian Syndromes Presenting with Homonymous Hemianopsia
Objective: We present here two cases of atypical parkinsonism with visual field loss to help increase recognition and drive research efforts forward to elucidate the…
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