The association of CSF sTREM2 with cognitive decline and its dynamic change in Parkinson’s disease: Analysis of the PPMI Cohort
Objective: This study aims to investigate the baseline and longitudinal changes of soluble fragments of triggering receptor expressed on myeloid cells 2 (sTREM2) in cerebrospinal…Disease knowledge in males and females with Parkinson’s Disease and Related Disorders
Objective: To examine sex differences in the knowledge base of Parkinson’s Disease and Related Disorders (PDRD) Background: Biologic sex accounts for differences in PDRD, not…Clinical characteristics in de-novo PD patients with reversible vs. progressive cognitive dysfunction during long-term follow-up
Objective: To compare clinical and imaging features in de-novo Parkinson’s disease (PD) with stable, remitting, and non-remitting cognition over 5 years follow-up. Background: Mild cognitive…Aerobic glycolysis regulates microglia-mediated neuroinflammation by promoting H3K9 lactylation in Parkinson’s disease
Objective: This study aims to investigate the role of histone lactylation in microglia-mediated neuroinflammation and dopaminergic (DA) neuronal damage in Parkinson’s disease (PD). Background: Augmented glycolysis induced by metabolic…Tremor as a Hallmark of Neurodegeneration and Mercury Intoxication
Objective: The aim of our study was to evaluate a computerized method for assessing tremor in neurodegenerative diseases and toxic effects of mercury, taking into…The impact of COVID-19 on Parkinson’s disease: a case-controlled registry and questionnaire study
Objective: The purpose of the study was to explore how having suffered through COVID-19 affects motor, nonmotor and general health aspects of Parkinson’s disease, and…Levodopa-induced unilateral orofacial dystonia in multiple system atrophy : case report and video presentation
Objective: The study reports a case of lateral orofacial dystonia in a multiple system atrophy (MSA) patient treated with levodopa, and discusses the clinical characteristics…To be or not to bupropion: a drug-induced parkinsonism?
Objective: To draw attention to drug-induced parkinsonism. Background: Although the main causes of parkinsonism are degenerative, there are some reversible causes, including drug-induced parkinsonism. Method:…Improvement of movement disorder and neurodevelopment under selegiline in a CLTC deficient patient
Objective: We report the significative improvement on both movement disorder and neurodevelopment in a 5-year-old CLTC deficient patient treated with selegiline. Background: In 2019 we described a 30-year-old woman…Impact of rs6265 in the Host and Donor on Dopamine Neuron Graft Function.
Objective: Extend investigations into the effect of the rs6265 single nucleotide polymorphism (SNP) on dopamine (DA) neuron graft efficacy using a parkinsonian rat model. Background:…
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