MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    Electrochemical skin conductance as a marker of autonomic failure in patients with Multiple System Atrophy

    S. Perez-Lloret, V. Fabry, F. Ory-Magne, C. Brefel-Courbon, A. Foubert-Samier, W. Meissner, O. Rascol, J. Senard, A. Pavy-Le Traon (Toulouse, France)

    Objective: We investigated the interest of a quick and non-invasive assessment of sweating as a marker of autonomic failure (AF) in Multiple System Atrohpy (MSA).…
  • MDS Virtual Congress 2020

    Treatment of Neurogenic Orthostatic Hypotension (nOH) in Multiple System Atrophy (MSA) with a wearable Pneumatic Compression Garment utilising Soft Robotics

    N. Sawal, H. Singh, A. Beri (Chandigarh, India)

    Objective: To use a novel Pneumatic Garment device for treatment of nOH in MSA. Background: nOH is present in 66-90% of patients with MSA and…
  • MDS Virtual Congress 2020

    Atypical Psychogenic Nonepileptic Seizure (PNES) preceding Multiple System Atrophy (MSA)

    A. Shahinian, T. Mehta, A. Betcher, P. Janda, J. Mahajan, A. Vickers (Las Vegas, NV, USA)

    Objective: To share a case report of Atypical PNES and MSA. Background: Multiple system atrophy (MSA) is a rare neurodegenerative diagnosis that clinically presents with…
  • MDS Virtual Congress 2020

    Cardiac Safety of PBT434, an Inhibitor of Alpha-Synuclein Aggregation for the Treatment of Multiple System Atrophy (MSA)

    D. Stamler, M. Bradbury, C. Wong, E. Offman (Newark, CA, USA)

    Objective: Evaluate potential cardiac liability of PBT434 using concentration-response and outlier analyses of ECG and pharmacokinetic (PK) data from a Phase 1 study of PBT434…
  • MDS Virtual Congress 2020

    GCI-induced neurodegeneration and synucleinopathy in non-human primates

    M. Teil, S. Dovero, M.L Artocarena, M. Bourdenx, G. Porras, B. Mollenhauer, M.T Herrero, M. Vila, J. Obeso, B. Dehay, E. Bezard (Bordeaux, France)

    Objective: This study aimed at determining the potential to induce MSA pathology in non-human primates. Background: Aggregation of alpha-synuclein has been implicated in several neurodegenerative…
  • MDS Virtual Congress 2020

    Endoscopic Characteristics of Swallowing Dysfunctions in Multiple System Atrophy

    A. Vogel, T. Warnecke, I. Claus, S. Ahring, D. Gruber, H.J Heinze, R. Dziewas, G. Ebersbach, F. Gandor (Beelitz-Heilstätten, Germany)

    Objective: To systematically assess frequency and characteristics of swallowing dysfunction in multiple system atrophy (MSA) patients during endoscopy and compare findings to a cohort of…
  • MDS Virtual Congress 2020

    Camptocormia in patients with multiple system atrophy with different disease durations

    L.Y Zhang, B. Cao, QQ. Wei, R.W Ou, H.F Shang (Chengdu, China)

    Objective: The aims of this study were to explore the prevalence of and factors associated with camptocormia in a cohort of multiple system atrophy (MSA)…
  • MDS Virtual Congress 2020

    Is brain perfusion a differentiating factor between Parkinson’s Disease (PD) and Progressive Supranuclear Palsy – Parkinsonism Predominant (PSP-P)?

    P. Alster, D. Koziorowski, L. Królicki, A. Friedman (Warsaw, Poland)

    Objective: Parkinson’s Disease – Postural Instability Gait Disorder (PD-PIGD) and Progressive Supranuclear Palsy – Parkinsonism Predominant (PSP-P) are entities affected by difficulties in differentiation in…
  • MDS Virtual Congress 2020

    Cognitive Differences Between Men and Women with Progressive Supranuclear Palsy

    E. Bayram, J. Jankovic, S. Reich, C. Marras, Y. Bordelon, D. Shprecher, R. Dubinsky, I. Litvan (La Jolla, CA, USA)

    Objective: (1) To evaluate the cognitive differences between men and women with progressive supranuclear palsy (PSP) and (2) to investigate whether sex has an effect…
  • MDS Virtual Congress 2020

    Correlations between amantadine usage, gait, and cognition in PSP: a post hoc analysis of the davunetide trial

    M. Dale, B. Brumbach, A. Hiller (Portland, OR, USA)

    Objective: Amantadine anecdotally improves gait and balance in PSP, potentially by increasing alertness, but there are no definitive data to support this observation. We investigated…
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