Pilot Study: Shear Wave Elastography as a Potential Biomarker in Task-Specific Dystonia
Objective: The purpose of this study was to explore shear wave elastography (SWE)’s ability to identify task-specific dystonic muscles by determining if muscle stiffness increased…Artificial Intelligence in the Early Detection of Parkinson’s Disease: Advances, Challenges, and Future Perspectives
Objective: This study reviews AI’s role in early PD detection, comparing AI-driven diagnostic methods with conventional clinical approaches in accuracy, reliability, and applicability. Background: Parkinson’s…Deep Learning-Driven Discovery of Mitochondrial Genomic Instability in Parkinson’s Disease: A Single-Cell Multi-Omics Approach
Objective: This study integrates snRNA-seq and proteomic data to (i) map mtDNA heteroplasmic mutations at single-cell resolution, (ii) identify mitochondrial-driven transcriptional dysregulation, and (iii) classify…Improved Outcomes for Patients with Autonomic Movement Disorders (AMD) Originally Evaluated for Psychogenic Non-Epileptiform Spells (PNES)
Objective: To evaluate whether treating underlying dysautonomia in patients with abnormal movements initially diagnosed with psychogenic non-epileptiform spells (PNES) leads to a reduction in motor…Dietary and Environmental Risk factors of Parkinson’s Disease: An integrated study combining Network Pharmacology and Molecular Docking Analyses
Objective: This large-scale case-control study using network pharmacology and molecular docking, aimed to identify dietary and environmental risk factors of Parkinson’s disease (PD). Background: PD…Validating Real-World Evidence for Identifying Adverse Events Related to a Deep Brain Stimulation Implant
Objective: This study aims to validate Real-world evidence (RWE) using claims-based algorithms to identify adverse events (AEs) among patients implanted with a Deep Brain Stimulation…Optimizing Bereitschaftspotential Detection Using Signal Processing Techniques
Objective: Apply signal processing methods for more robust Bereitschaftspotential detection Background: The Bereitschaftspotential (readiness potential, BP) is a small, slow rising negative scalp EEG potential…The Phenomena of “Meryacheniye” and “Kliukushestvo” in Yakutia in the 20th Century
Objective: To review the characteristics of psychogenic movement disorders in Yakutia. Background: At the beginning of the 20th century, the conditions known as “meryacheniye” and…CAPOS Phenotypic Spectrum: CAPOS, CAPOS+ and CAPOS- within the p.Glu831Lys Variant of the ATP1A3 gene. Case Report and Literature Review.
Objective: To describe and compare the clinical phenotype and frequency of symptom presentation of p.Glu831Lys variant associated syndrome within the ATP1A3 gene, adding the first…Physical, Mental, and Socioemotional Functional Improvement Following Valbenazine Treatment for TD: a Case Series
Objective: Describe clinical characteristics and changes in mental, socioemotional, and physical domains of individuals with tardive dyskinesia (TD) after valbenazine (VBZ) treatment. Background: Prior research…
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