Transcranial Magnetic Stimulation as Treatment for Functional Movement Disorders: Experiences from a Single Centre Retrospective Audit
Objective: St Vincent’s Hospital Sydney has been offering Transcranial Magnetic Stimulation (TMS) to adult patients with a diagnosis of Functional Movement Disorders (FMD) since 2020.…Tourette – Like Phenotypes Following Combined Striatal Interneuron Loss.
Objective: To determine whether the ablation of Nkx2.1 derived striatal interneurons (SI) in mice produces Tourette-like phenotypes including abnormal movements and perseverative behaviors. Background: Tourette…Neuroprotective Effects of Co-Administered Hesperetin and Resveratrol Nanoparticles on Oxidative Stress and Neurobehavioral Deficits in Parkinson’s Disease
Objective: This study aimed to evaluate the therapeutic potential of solid lipid nanoparticles (SLNs) containing hesperetin (HE-SLN), resveratrol (RE-SLN), and their co-administration (HE-RE-SLN) in combating…SREAT with Cerebellar Involvement: When Tremor Mimics Stroke – A Case report
Objective: To describe a patient with SREAT in whom an initial diagnosis of a stroke was made Background: Acute ataxia is a clinical setting where…Artificial Intelligence in the Early Detection of Parkinson’s Disease: Advances, Challenges, and Future Perspectives
Objective: This study reviews AI’s role in early PD detection, comparing AI-driven diagnostic methods with conventional clinical approaches in accuracy, reliability, and applicability. Background: Parkinson’s…Deep Learning-Driven Discovery of Mitochondrial Genomic Instability in Parkinson’s Disease: A Single-Cell Multi-Omics Approach
Objective: This study integrates snRNA-seq and proteomic data to (i) map mtDNA heteroplasmic mutations at single-cell resolution, (ii) identify mitochondrial-driven transcriptional dysregulation, and (iii) classify…Neurodegenerative Langerhans Cell Histiocytosis: A Rare Cause of Cerebellar Ataxia
Objective: To describe a rare case of progressive cerebellar ataxia due to neurodegenerative Langerhans Cell Histiocytosis (ND-LCH) and highlight diagnostic challenges with atypical imaging findings.…Dietary and Environmental Risk factors of Parkinson’s Disease: An integrated study combining Network Pharmacology and Molecular Docking Analyses
Objective: This large-scale case-control study using network pharmacology and molecular docking, aimed to identify dietary and environmental risk factors of Parkinson’s disease (PD). Background: PD…Challenges in the Diagnosis and Management of Functional Movement Disorders in a Developing Nation: Insights from the Philippines
Objective: To systematically analyze patient data to explore the clinical phenotypes, risk factors, management, and outcomes among patients with functional movement disorders (FMD) in the…Unraveling Functional Overlay in Parkinson’s Disease: A Diagnostic Challenge
Objective: To highlight the diagnostic complexities of functional movement disorders (FMD) in Parkinson’s disease (PD) and the role of neurophysiological studies in differentiating functional overlay…
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