MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Simple linear measurements of the putamen reliably differentiate MSA from other parkinsonian disorders on MRI.

    T. Rohringer, V. Lam Shin-Cheung, P. Alcaide-Leon (Toronto, Canada)

    Objective: This study evaluates the utility of simple linear measurements of the putamen to distinguish Multiple System Atrophy (MSA) from idiopathic Parkinson’s Disease (iPD) and…
  • 2025 International Congress

    Neuroprotective efficacy of EDTA against manganese neurotoxicity: Implications for modulating Parkinsonian syndromes

    H. Harifi, H. Hami, L. Bikjdaouene (Kenitra, Morocco)

    Objective: This study investigates the neuroprotective potential of ethylenediaminetetraacetic acid (EDTA) in reducing the neurotoxic effects of manganese (Mn), focusing on both motor and non-motor…
  • 2025 International Congress

    Clinical and Dopaminergic Characteristics of MSA-C Patients with Predominant Cerebellar Asymmetry

    DG. Park, YS. Kim, YS. An, JH. Yoon (Suwon, Republic of Korea)

    Objective: To identify multiple system atrophy–cerebellar type (MSA-C) patients with marked cerebellar asymmetry and compare their features with symmetrically affected patients. Background: While asymmetry is…
  • 2025 International Congress

    Normal Pressure Hydrocephalus in Vestibular Schwannoma Patients

    T. Davidy, S. Anis, T. Goldberg, A. Fay-Karmon, Y. Zauberman, N. Rennert, O. Lesman-Segev, S. Hassin-Baer (Cleveland, USA)

    Objective: The first objective is to evaluate the potential pathophysiological link between vestibular schwannoma (VS) and normal pressure hydrocephalus (NPH) by analyzing clinical features, imaging…
  • 2025 International Congress

    A rapidly progressive multiple system atrophy-cerebellar variant model presentingα-synuclein oligomer spreading and phosphorylated α-synuclein aggregate formation accompanied with glial inflammation

    D. Matsuse, H. Yamaguchi, Y. Nishimura, H. Sekiya, K. Masaki, T. Tanaka, T. Saiga, M. Harada, K. Kira, D. Dickson, K. Fujishima, E. Matsuo, K. Tanaka, R. Yamasaki, N. Isobe, J. Kira (Fukuoka, Japan)

    Objective: We aimed to develop a rapidly progressive mouse model that recapitulates MSA-C pathology. Background: Multiple system atrophy (MSA) is a severe α-synucleinopathy driven by…
  • 2025 International Congress

    Case report and Literature Review on Atypical Parkinson’s Disease

    MJ. Dashdorj (Ulaanbaatar, Mongolia)

    Objective: Atypical parkinsonism is classified as a subgroup of Progressive neurodegenerative diseases, characterized by symptoms of Parkinson's disease. Background: Progressive supra nuclear palsy of the…
  • 2025 International Congress

    Clinical subtypes and Radiological patterns in Progressive supranuclear palsy: A Prospective study

    K. Gulati, S. Pandey (Faridabad, India)

    Objective: To subclassify Progressive supranuclear palsy (PSP) into cortical and subcortical typesTo identify the clinical and radiological correlation in PSP Background: The 2017 International Parkinson…
  • 2025 International Congress

    Neuroinflammatory response is determined by HLA genotype in progressive supranuclear palsy

    G. Kovacs, H. Chasiotis, S. Zaheer, J. Wang, J. Li, MC. Tartaglia, S. Fox, A. Lang, S. Forrest (Toronto, Canada)

    Objective: Our aim was to examine whether the HLA haplotypes influence the neuroinflammatory response in a cohort of neuropathologically diagnosed PSP cases. Background: Progressive supranuclear…
  • 2025 International Congress

    Cutaneous Phosphorylated Alpha-Synuclein Deposition in Multiple System Atrophy

    R. Freeman, T. Levine, B. Bellaire, C. Gibbons (boston, USA)

    Objective: To report differences in the amount, localization and topographic distribution of cutaneous P-SYN deposition between cerebellar and parkinsonian variants of MSA. Background: MSA is…
  • 2025 International Congress

    Connectome of Pathology Stages of Progressive Supranuclear Palsy

    N. Vallenas, H. Tanaka, S. Lee, G. Kovacs, B. Couto (New York, USA)

    Objective: Find the relations between normative FC and seed-to-seed correlations in pathological tau load. Model the FC maps for twelve patients, using post-mortem tau pathology…
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