Interim Report of Quality of Life Outcomes After Deep Brain Stimulation for Parkinson’s Disease from a Large Global Real-World Study
Objective: To summarize quality of life outcomes after 2 years of deep brain stimulation (DBS) for Parkinson’s disease (PD). Background: DBS improves motor fluctuations associated…TRPV1: A Potential Therapeutic Target for Inflammation and Pain in Parkinson’s Disease
Objective: Unveiling the Pain Mechanism in Parkinson's Disease: A Path to New Therapies Background: Parkinson's disease (PD) are well-known movement disorder. While motor symptoms are…Molecular Landscape of Gastrointestinal Dysfunctions in Parkinson’s Disease
Objective: Analyze multi-omics data from the PPMI cohort to identify molecular markers associated with self-reported gastrointestinal (GI) dysfunction in Parkinson's disease (PD) patients. Background: PD…Exploring Supervised and Real-World Mobility in People with Parkinson’s Disease with and without Nocturnal Hypokinesia
Objective: To evaluate supervised and real-world mobility in people with Parkinson’s disease (PwPD) with and without nocturnal hypokinesia (NH). Background: Mobility impairment and NH are…18F-Florzolotau Positron Emission Tomography Imaging Correlates with Regional Brain Atrophy and Plasma Biomarkers in Tauopathy Parkinsonism Syndrome
Objective: We aim to investigate the relationship between regional 18F-florzolotau uptake and clinical severity, structural volume changes, and plasma markers in tauopathy parkinsonism syndrome. Background:…Dysphagia is Frequent in early Parkinson´s Disease. Results from a 5-year Follow-up Study.
Objective: The aim of the present study was to analyze the frequency of dysphagia in patients with early Parkinson´s disease (PD) and to compare with…Gender-Based Differences in Sleep Quality Among Hispanic Parkinson’s Disease Patients
Objective: The study aims to evaluate sleep quality among male and female Hispanic PD patients using the Parkinson's Disease Sleep Scale (PDSS) Background: Parkinson's disease (PD) is acknowledged for its multifaceted…Exploring Retrospectively the Predisposing Factors of Sleep Disorders in Parkinson’s Disease.
Objective: Identify the predisposing or exacerbating factors of sleep disorders in Parkinson's disease, and examine their association with levodopa treatment. Background: Parkinson's disease (PD) is…Familial Multiple System Atrophy-Mimics: Importance of Comprehensive Evaluation
Objective: We present two patients initially diagnosed as familial MSA until one of the patients was proven to be metachromatic leukodystrophy (MLD). Background: Multiple system…Dissecting Neural Circuits Regulating Sleep State Transitions in a Mouse Model of Parkinson’s Disease
Objective: To examine sleep architecture in a commonly studied mouse model of Parkinson’s disease (PD) to better understand underlying circuit mechanisms of sleep disturbances in…
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