MDS Abstracts

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STN DBS can temporarily improve balance disorders in Parkinson’s disease (PD) patients.

S. Szlufik, M. Kloda, I. Potrzebowska, K. Gregier, A. Friedman, A. Przybyszewski, J. Dutkiewicz, P. Habela, T. Mandat, D. Bialoszewski, D. Koziorowski (Warsaw, Poland)

Meeting: 2017 International Congress

Abstract Number: 376

Keywords: , ,

Session Information

Date: Monday, June 5, 2017

Session Title: Surgical Therapy: Parkinson’s Disease

Session Time: 1:45pm-3:15pm

Location: Exhibit Hall C

Objective: The aim of this study was to evaluate the impact of STN DBS on balance disorders in PD patients.

Background: Subthalamic nucleus deep brain stimulation (STN DBS) can influence on balance and gait disorders, but there are some conflicting information.

Methods: DBS-group consisted of 20 PD patients (7F,13M) who underwent bilateral STN DBS. POP-group consisted of 15 post-DBS PD patients (6F,9M) in median 24 month-time after surgery. Control group (MED-group) consisted of 24 patients (13F,11M) who did not underwent surgical intervention. UPDRS III scale and balance tests (UpAndGo Test, Tandem Walk Test) were measured during 3 visits (V1, V2, V3) in total OFF phase. The mean period between visits was 9±3months.

Results: We have observed the improvement in balance tests (UpAndGo, TWT) in V2/V1 DBS-group period (p<0,05) which was not observed in other (MED, POP) groups. The effect was not observed in V3/V2 DBS-group period. The comparable UPDRS III changes were also observed in V2/V1 (p<0,05) vs V3/V2 (p>0,05) DBS-group periods whereas V3/V2/V1 in MED-group and POP-group UPDRS III OFF scores were statistically changed (p<0,05).

Conclusions: STN DBS can temporarily improve balance disorders in PD patients, with the strongest effect during first 6 postoperative months.   

To cite this abstract in AMA style:

S. Szlufik, M. Kloda, I. Potrzebowska, K. Gregier, A. Friedman, A. Przybyszewski, J. Dutkiewicz, P. Habela, T. Mandat, D. Bialoszewski, D. Koziorowski. STN DBS can temporarily improve balance disorders in Parkinson’s disease (PD) patients. [abstract]. Mov Disord. 2017; 32 (suppl 2). https://www.mdsabstracts.org/abstract/stn-dbs-can-temporarily-improve-balance-disorders-in-parkinsons-disease-pd-patients/. Accessed June 15, 2025.

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