VANTAGE trial: Three year outcomes of a prospective, multi-center trial evaluating deep brain stimulation with a new multiple-source, constant-current rechargeable system in Parkinson’s disease
Objective: The VANTAGE study assesses motor improvement in moderate-to-severe Parkinson's disease (PD) following bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) using a new, implantable,…Duodenal levodopa infusion: Safety and efficacy in a 6 years outpatient follow-up
Objective: To reduce the risk of adverse events and dropout rate in patients. Background: Duodenal levodopa infusion (DLI) is used for the treatment of advanced…Patient experiences following Parkinson’s disease treatment with inhaled levodopa: Results from a Phase 2b study
Objective: To report patient experiences from a clinical trial investigating Parkinson's disease (PD) control following treatment with inhaled levodopa. Background: CVT-301, an inhaled levodopa powder…A survey of impulse control disorders in Chinese patients with Parkinson’s disease and literature review
Objective: This study aims to investigate the incidence of ICD in Chinese PD patients from Shanghai area, explore the association of ICD with dopamine replacement…Utilizing remote blood pressure monitoring in a phase III clinical drug trial for Parkinson’s disease
Objective: To determine the feasibility and value of remote blood pressure (BP) monitoring during a clinical trial of isradipine (a dihydropyridine calcium channel antagonist) in…Regional differences in the results of a phase 2b study of tozadenant in Parkinson’s disease patients with motor fluctuations
Objective: To assess how the efficacy of tozadenant differed by region in a randomized, double-blind, placebo-controlled trial of Parkinson's disease patients with motor fluctuations. Background:…The study of clinical outcome of deep brain stimulation for the idiopathic Parkinson’s disease at 6 months follow-up
Objective: The aim of this study was to assess the motor and psychiatric outcomes at 6 months after subthalamic nucleus deep brain stimulation (STN-DBS) in…Difference between physiologically defined subthalamic nucleus target and final lead placement: Influence in clinical outcome
Objective: To evaluate distance between the physiologically defined subthalamic nucleus (STN) target and final lead placement, and its influence on the clinical outcome at 6…Successful DBS: Doctors happy, patients not – Why?
Objective: Deep brain stimulation (DBS) in Parkinson's disease (PD) has been proven successful; however, not in all. Background: We report on 5 PD patients who…Comparison of four DBS lead designs under voltage and current operating modes based on patient specific simulations
Objective: To quantitatively compare the spatial extension of the electric field generated by four different lead designs operated under voltage and current modes. Background: Conventional…
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