MEK inhibitors have antidyskinetic effects in hemiParkinsonian rats that are associated with critical neurochemical alterations in the striatum
Objective: To examine the effects of MEK inhibitors PD98059 and U0126 on L-DOPA-induced dyskinesia and the induced molecular changes. Background: L-DOPA-induced dyskinesia (LID) represents one…Opsoclonus myoclonus ataxia syndrome in a seronegative patient with disseminated cryptococcosis: The first case report
Objective: To describe a 56-year-old man who presented with OMA due to disseminated cryptococcosis. Background: Opsoclonus-myoclonus-ataxia syndrome (OMA) is a rare neurological syndrome,characterized by a…Sleep motor activity in amyotrophic lateral sclerosis
Objective: To analyze quantitatively and with the most recent and advanced tools the presence of periodic leg movements during sleep (PLMS) PLMS and/or REM sleep…Tick disorders in children and differential diagnosis with progressive diseases of the nervous system
Objective: Objective of the study was investigating th neurological, neurochemical, neuroimaging and psychological features of children (5 to 15 years) with chronic tic disorder. Background:…Essential tremor: Characterization according to their phenotypes and their association with Parkinsonian signs
Objective: To evaluate clinical and neurophysiological features of ET and their phenotypes: classic (ET/Cl), ET with resting tremor (ET/RT), head (ET/H), voice (TE/V), chin (ET/Ch),…To new method of tremor assessment
Objective: To develop a new approach to quantitative assessment of Parkinson's tremor based on the calculation of the area of recorded wave of tremor at…Regulation in speech motor control in ET patients treated with DBS: Kinematics of the lingual and the labial systems
Objective: We aim to quantify the effects of VIM-DBS on speech regulation mechanisms in patients with Essential Tremor (ET). Background: VIM-DBS is an effective treatment…Substantia nigra α4β2 nicotinic cholinergic receptor expression correlates with tremor in Parkinson’s disease
Objective: To investigate the relationship between tremor and α4β2 nicotinic cholinergic receptor (nAChR) expression in brain regions associated with tremor in Parkinson's disease (PD), including…Movement disorders are the common signs as the first neurological deficit in cases with spinocerebellar ataxia type 2 (SCA2)
Objective: We studied neurological signs in cases with SCA2 for early diagnosis. Background: SCA2 is a classification of hereditary ataxia, however, patients with SCA2 have…Can quantitative analysis of the “finger-to-nose test” discern between EOA and other conditions of coordination impairment?
Objective: In Early Onset Ataxia (EOA), we investigated whether quantitative analysis employing motion sensors could provide reliable and discriminative outcomes. Background: Many pediatric conditions can…
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