Hypothalamic alpha-synuclein pathology and its relation to non-motor symptoms and disease progression in Parkinson’s disease
Objective: To assess alpha-synuclein pathology and tyrosine hydroxylase (TH) immunoreactivity as a dopaminergic marker in three hypothalamic nuclei with potential clinical implications (paraventricular, supraoptic and…Chronic levodopa treatment accelerates the disorders of circadian rhythm in 6-OHDA induced Parkinson’s disease model
Objective: We aimed to study the effect of levodopa on circadian rhythms in 6-OHDA lesioned rats, and to clarify whether the disturbance of the circadian…Idiopathic Parkinson’s disease presenting with dysphagia 15 years before PD diagnosis
Objective: To describe an atypical presentation of Idiopathic Parkinson's disease. Background: Dysphagia is a commonly reported “non-motor” feature of Idiopathic Parkinson's disease (IPD), which usually…Anxiolytic-like activity of the adenosine A2A receptor antagonist, istradefylline (KW-6002) in rodent models of anxiety
Objective: The aim of this study was to assess the anxiolytic effects of istradefylline (KW-6002), an adenosine A2A receptor antagonist, in naive and anxiety-prone animals…Measurement of night time sleep using an accelerometry based system
Objective: To establish whether accelerometry using the Parkinson Kinetigraph (PKG, Global Kinetics) can distinguish between normal and abnormal nocturnal sleep in Parkinson's disease (PD). Background:…Exploring association of GBA variants with pre-diagnostic features of PD in the PREDICT-PD cohort: A nested case-control study
Objective: To investigate the association of GBA variants with pre-diagnostic features of Parkinson's disease (PD) within the PREDICT-PD cohort. Background: Subtle motor and non-motor symptoms…Neuropsychological assessment in the Luxembourg Parkinson’s cohort (HELP-PD)
Objective: To report first results on the prevalence of cognitive non-motor symptoms in the Luxembourg Parkinson's cohort (HELP-PD). Background: HELP-PD aims to combine thorough assessment…Parkinsonism risk factors in Salt Lake City, Utah
Objective: To assess the prevalence of risk factors for parkinsonism in Salt Lake City (SLC), Utah. Background: Recent data suggest that non-motor symptoms including constipation,…Dynamics in statin use, low density lipoprotein cholesterol levels and Parkinson’s disease. A population-based cohort study using big-data
Objective: To evaluate the association between time-varying statin use and PD risk in a large-scale population-based study. Background: Statins have been shown to downregulate neuroinflammation,…Appendicitis and risk of Parkinson’s disease: A Danish nationwide population-based cohort study
Objective: To examine the long-term association between appendicitis and risk of Parkinson's disease (PD) we conducted a population-based cohort study using prospectively collected registry data…
- « Previous Page
- 1
- …
- 114
- 115
- 116
- 117
- 118
- …
- 207
- Next Page »