Adenosine A2A receptor antagonist istradefylline might have efficacy to fatigue and depression in some patients of Parkinson’s disease
Objective: To evaluate the efficacy of istradefylline, a selective adenosine A2A receptor antagonist, for fatigue and depression in Parkinson's disease (PD) patients. Background: Istradefylline is…Switching double-blind opicapone, entacapone or placebo to open-label opicapone: Efficacy results of the 1-year extension of study BIPARK I
Objective: Evaluate the efficacy of opicapone (OPC) in Parkinson's disease (PD) patients with motor fluctuations enrolled in the 1-year extension of study BIPARK I. Background:…Speech and voice range profile in patients with Parkinson’s disease with deep brain stimulation: Preliminary data
Objective: To assess the use of Voice Range Profile(VRP) and Speech Range Profile(SRP) in the evaluation of patients with on and off Deep brain stimulation(DBS).…Improving drug discovery using brain oscillations as biomarkers of Parkinson’s disease
Objective: The aim of this study was to assess the use of cortical oscillations as translational biomarkers for drug development for the motor symptoms of…The potential therapeutic effect of intranasal administration of stem cells in rotenone model of Parkinson’s disease in mice
Objective: In this study we assessed the potential beneficial effect of intranasal administration of mesenchymal stem cells (MSCs) to rotenone model of PD in C57bl/6…Utility of IgGs subtypes in hemolytic anemia prevention and treatment maintenance in patients treated with continous infusion of apomorphine
Objective: The objetive of our study is to assess the utility of the subtypes IgG direct Coombs test (DCT) in maintenance apomorphine treatment without risk…Expiratory muscle training for the impaired loudness of speech in Parkinson’s disease: An open-label study
Objective: To investigate the efficacy of EMT for the impaired loudness of speech in patients with PD, we conducted an open-label pilot trial of EMT.…Does physical exercise influence the cognitive domains that predict dementia in Parkinson’s disease?
Objective: This study aimed to investigate the effects of aerobic and goal-based exercise on memory, language, and visuospatial functions in cognitively normal and impaired individuals…Body position during sleep in patients with Parkinson’s disease (PD): A sensor-based analysis
Objective: To identify the body position during sleep in PD patients in comparison to their spouses by using multisite wearable inertial sensors. Background: Nocturnal hypokinesia…The Parkinson progression marker initiative (PPMI) – Developing a comprehensive longitudinal biomarker dataset
Objective: The goal of the Parkinson Progression Marker Initiative (PPMI) is to identify clinical, imaging and biospecimen biomarkers of PD progression to provide tools for…
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