Disease stage classification of the cerebellar variant of multiple system atrophy based on voxel-based morphometry
Objective: We previously reported that voxel-based morphometry (VBM) is effective for classifying the disease types causing cerebellar atrophy. In the present study, with the objective…Quantitative MRI measurement of regional cerebellar involvement in patients with progressive supranuclear palsy
Objective: We aimed to evaluate cerebellar involvement in PSP using MRI segmental volumetric analysis. Background: Progressive supranuclear palsy (PSP) is characterized clinically as postural instability…Impaired hippocampal neurogenesis associates with serotonergic axonal degeneration in transgenic rat and mouse models of Parkinson’s disease
Objective: To evaluate the impact of α-synuclein accumulation on the hippocampal serotonergic system and hippocampal plasticity in two different α-synuclein expressing rodent models. Background: Parkinson's…Vitamin D in early Parkinson’s disease
Objective: To determine serum 25-hydroxy vitamin D (25OHD) concentration at diagnosis and 18 months in incident Parkinson's disease (PD) compared to controls and to investigate…Tau dysfunction in the basal ganglia of a mouse model of tauopathy related to PSP
Objective: Determine motor coordination and neurochemical phenotypes in the basal ganglia of mice lacking the Tau protein or expressing an abnormal content of Tau isoforms.…An elderly patient presenting as pure akinesia with gait freezing (PAGF): Idiopathic aqueductal stenosis-associated hydrocephalus
Objective: Pure akinesia with gait freezing (PAGF)-mimicking disorders remain to be further elucidated. Background: Hydrocephalus is a poorly elucidated disorder. Aqueductal stenosis (AS) is a…Drug induced parkinsonism: Role of functional imaging and follow up
Objective: Retrospective study of the outcome of patients with new onset parkinsonism with a history of exposure of a drug known to cause parkinsonism prior…Creative thinking and parkinsonism: Preliminary clinical data on the role of frontal area
Objective: To evaluate divergent thinking (DT) by means of Abbreviated Torrance Test for Adults (ATTA) in Parkinsonism (PKS) with different deficit in cognitive functions. Background:…Brain structural abnormalities in multiple system atrophy patients with cognitive impairment
Objective: To investigate the cerebral anatomical changes associated with cognitive impairment (CI) in multiple system atrophy (MSA). Background: Mild cognitive deficits are frequently reported in…Parkinsonism in patients with CADASIL
Objective: To report the clinical manifestation of parkinsonism in patient with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) confirmed by the NOTCH3…
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