Generation and characterization of iPSC-derived nigral dopaminergic and pyramidal glutamatergic neurons from patients affected by multiple system atrophy
Objective: The aim of the present study is to generate dopaminergic and pyramidal neurons from iPSCs of MSA patients in order to establish an in…Triple stimulation technique findings in patients with Parkinson’s disease and multiple system atrophy
Objective: This study aims to evaluate the cortico-spinal tract impairment in PD and multiple system atrophy (MSA) Parkinsonian variant using triple stimulation technique (TST). Background:…Multiple system atrophy: A comparison between clinical subtypes
Objective: To evaluate the cognitive impairment and sleep disturbances in subtype MSA-P versus MSA-C. Background: Multiple system atrophy (MSA) is a progressive neurodegenerative disorder of…Non-motor symptoms in a PPMI cohort of p.A53T α-synuclein mutation-related and sporadic Parkinson’s disease patients
Objective: To evaluate the prevalence of non-motor symptoms in p.A53T α-synuclein (SNCA) related Parkinson's disease (PD) as compared to sporadic Parkinson's disease (sPD) patients. Background:…Increased monosaccharide intake in patients with Parkinson’s disease
Objective: To verify the clinical observation that patients with Parkinson's disease (PD) have a higher consumption of monosaccharides. Background: Patients with PD frequently report an…Unusual motor and non-motor symptoms and signs in the early stage of Parkinson´s disease
Objective: To present unusual motor and non-motor symptoms and signs in the early stage of Parkinson´s disease. Background: Patients with Parkinson´s disease (PD) may present…The influences of STN-DBS and levodopa on cardiovascular autonomic function in patients with Parkinson’s disease: Evaluated by trigonometric regressive spectral analysis
Objective: To explore the effects of STN-DBS and levodopa on cardiovascular autonomic function in PD. Background: Cardiovascular autonomic dysfunction has been shown in patients with…Diagnostic value of combined acute levodopa challenge and olfactory testing to predict Parkinson’s disease diagnosis
Objective: To evaluate the diagnostic value of combined acute levodopa challenge and olfactory testing to predict PD diagnosis. Background: Acute levodopa challenge can be used…Sleep disordered breathing in patients of Parkinson’s disease with REM sleep behavior disorder
Objective: This prospective study was done to study the frequency and pattern of sleep disordered breathing (SDB) in patients with PD with RBD. Background: Parkinson's…A computerized cognitive behavioral therapy randomized, controlled, pilot trial for insomnia in Parkinson’s disease (The ACCORD-PD study)
Objective: To demonstrate benefit of computerized cognitive behavioral therapy for insomnia (CCBT-I) in Parkinson's disease (PD) patients. We are unaware of any study on CCBT-I…
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