- Stage dependent alteration of cortical excitability in patients with hepatic encephalopathyObjective: To evaluate cortical excitability in patients with hepatic encephalopathy (HE) using transcranial magnetic stimulation (TMS). Background: HE is a neuropsychiatric disorder manifesting with movement…
- Resting-state functional connectivity of subthalamic nucleus in different phenotypes of Parkinson’s diseaseObjective: To explore the different resting-state functional connectivity of subthalamic nucleus (STN) in different phenotypes of Parkinson's disease (PD). Background: The STN is one of…
- Correlation analysis for postural instability and autonomic dysfunction in patients with Parkinson’s diseaseObjective: To investigate correlation between postural instability and autonomic dysfunction in early stage Parkinson's disease patients. Background: Brainstem pathology may link postural instability (PI) and…
- When and why patients with Parkinson’s disease become bed riddenObjective: To elucidate the influence of age, disease duration, and complicated medical and social conditions as the risk factors to predict disease progression. To this…
- Diagnostic value of a new coronal examination plane in transcranial nigral sonography and of additional M-mode tremor frequency determination for the differentiation of idiopathic Parkinson’s disease and essential tremorObjective: To (1) evaluate a new coronal examination plane in comparison to the established axial examination plane for detection of nigral hyperechogenicity and (2) to…
- Impaired cerebellum to motor cortex associative plasticity in Parkinson’s diseaseObjective: To compare the corticocortical paired associative stimulation (PAS)-induced spike-timing dependent plasticity (STDP)-like plasticity between Parkinson's disease (PD) and healthy elder subjects. Background: Patients with…
- Pain-motor integration in the primary motor cortex in Parkinson’s diseaseObjective: To investigate pain-motor integration experimentally in patients with Parkinson's disease (PD), with and without chronic pain. Background: Although chronic pain is a common non-motor…
- Combined effects of visual and auditory cues on gait initiation in Parkinson’s diseaseObjective: To investigate the combined effects of visual and auditory cues on gait initiation and to investigate the correlation between the clinical rates of gait…
- Novel PET Tracers of alpha-synuclein for the diagnosis of Parkinson’s diseaseObjective: The aim of our project is to develop small molecular weight compounds (Morphomers™) which bind selectively to alpha-synuclein (aSyn) aggregates, in order to generate…
- DTI in Parkinson’s disease: Asymmetric progressionObjective: To study the rate of change of brain region diffusion tensor imaging (DTI) parameters between the right and left sides in PD patients using…
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