MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Lymphocytes have a detrimental effect on motor behavior in the AAV1/2 A53T α-synuclein mouse model of Parkinson’s disease

    A.A. Karikari, M. Gehmeyr, E. Ribechini, V. Maltese, J. Volkmann, J.M. Brotchie, J.B. Koprich, M.B. Lutz, C.W. Ip (Würzburg, Germany)

    Objective: To determine the contribution of the adaptive immune system in the pathogenesis of a mouse model of Parkinson's disease (PD) based on AAV1/2 driven…
  • 2016 International Congress

    Dynamic and static posturographic analysis among fallers and non- faller Parkinson’s disease (PD) patients using Neurocom SMART EquiTest

    A. Lieberman, C. Frames, A. Deep, M. McCauley, S. Shafer (Phoenix, AZ, USA)

    Objective: The purpose of this investigation is to study both the sensory and motor aspects of voluntary and automatic postural control using static and dynamic…
  • 2016 International Congress

    Mild mitochondrial impairment promotes corticostriatal synaptic plasticity alterations in PINK1 heterozygous knockout mice

    P. Imbriani, G. Martella, G. Madeo, M. Maltese, V. Vanni, E. Ferraro, E.M. Valente, T. Schirinzi, L. Bonanni, J. Shen, N.B. Mercuri, P. Bonsi, A. Pisani (Rome, Italy)

    Objective: To investigate the effects of the exposure to low-dose rotenone of heterozygous PINK1 knockout (PINK1+/-) mice, compared to their wild-type littermates (PINK1+/+), on dopamine-dependent…
  • 2016 International Congress

    Sodium butyrate attenuates rotenone-induced neurodegeneration via enhancing autophagy and preventing α-synuclein aggregation

    L. Liu, C. Han, K. Ma, X. Xu, J. Huang, N. Xiong, T. Wang (Wuhan, People's Republic of China)

    Objective: To investigate whether sodium butyrate (NaB) could enhance autophagy and thus exert a neuroprotective effect through the modulation of α-synuclein in animal models of…
  • 2016 International Congress

    Molecular landscape of Parkinson’s disease reveals a key role for lipids and lipoproteins

    C.J.H.M. Klemann, G.J.M. Martens, M. Sharma, M.B. Martens, O. Isacson, T. Gasser, J.E. Visser, G. Poelmans (Nijmegen, Netherlands)

    Objective: Integrate available genetic and expression data to generate a molecular landscape of Parkinson's disease (PD) in order to identify key disease mechanisms that may…
  • 2016 International Congress

    Cortical role in the freezing of gait in Parkinson’s disease

    M. Mihara, H. Otomune, H. Fujimoto, K. Konaka, Y. Watanabe, H. Mochizuki (Suita, Japan)

    Objective: In this study, we aimed to investigate the neural underpinning of freezing of gait (FOG) in Parkinson's disease (PD), especially the role of the…
  • 2016 International Congress

    Manganese-induced parkinsonism and motor neuron damage- Can there be a relationship?

    I. Giorgishvili, N. Lobjanidze, N. Akiashvili, M. Janelidze, M. Beridze (Tbilisi, Georgia)

    Objective: The aim of the study was evaluation of clinical, radiological and ENMG characteristic of ephedronic encephalopathy(EE). Background: The ephedrone abuse is widely spread among…
  • 2016 International Congress

    Fahr’s syndrome in a Filipino female with hearing loss and polycystic ovaries: A case report

    P.D. Dadgardoust, R.L. Rosales (Manila, Philippines)

    Objective: The objective of this case report is to document a case of Fahr's syndrome including its varied clinical manifestations. Background: Idiopathic basal ganglia calcification,…
  • 2016 International Congress

    A peripheral pathway to restless legs syndrome? Clues from familial amyloid polyneuropathy

    T. Teodoro, P. Viana, D. Abreu, I. Conceição, R. Peralta, J.J. Ferreira (Lisboa, Portugal)

    Objective: To investigated if RLS is increased in familial amyloid polyneuropathy related to transthyretin (TTR-FAP) and to identify factors associated with RLS in this population.…
  • 2016 International Congress

    SPAsticity in PractiCE (SPACE) – An international, observational study of botulinum toxin type A in spasticity

    J. Wissel, J. Harriss, O. Simon, K. Sternberg, N. Roche, C. Cantú-Brito, S. Khatkova, P. Säterö (Berlin, Germany)

    Objective: To collect real-world routine clinical practice data on effectiveness, safety, and quality of life (QoL) for botulinum toxin type A (BoNT-A) treatment of focal…
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