Cognitive impairment in Huntington’s disease
Objective: The present study was done to assess cognitive impairment in HD patients using a neuropsychological battery and to correlate with clinical severity and CAG…Demographic and phenotypic comparison of Huntington’s disease in Europe and North America: Data from REGISTRY and COHORT, two prospective observational cohort studies
Objective: We tested the assumption that the demographic and clinical spectrum of Huntington's disease (HD) is fairly similar irrespective of the geographical region of origin…Clinical and behavioral features in carriers of intermediate length alleles of HTT gene. A case series of Mexican population
Objective: To describe clinical manifestations in carriers of intermediate alleles (IAs) of CAG trinucleotides in HTT gene of Mexican population. Background: Huntington's disease (HD) is…Severe striatal and pallidal atrophy in early disease stages of X-linked dystonia-parkinsonism
Objective: To investigate cortical and subcortical atrophy patterns in X-linked dystonia-parkinsonism (XDP). Background: XDP is a neurodegenerative disorder characterized by severe adult-onset dystonia followed by…Globus pallidus interna oscillatory activity differentiates tics from voluntary movements and the Parkinsonian resting state
Objective: To describe local field potential (LFP) characteristics during tic acivity, voluntary activity, and the Parkinsonian resting state. Background: Deep brain stimulation is an emerging…Disruption of functional connectivity in Parkinson’s disease patients presenting phonemic fluency impairment
Objective: This study was designed to clarify the changes of detailed functional connectivity in association with phonemic fluency deficits in Parkinson's disease (PD) patients using…Gray/white matter contrast loss correlates with clinical severity and visuospatial impairment in Parkinson’s disease patients
Objective: The aim of our study was to test if PD patients differ from healthy controls (HC) in GWR and if this MRI parameter has…Risk factors of wearing-off phenomenon in Parkinson’s disease in Japan
Objective: Parkinson's disease (PD) is one of common progressive neurodegenerative disorder involving nigrostriatal dopaminergic neurons. The aim of this study was to investigate risk factors…Diverse effects of alpha-synuclein fibrils on various neuron cell lines, using different buffers
Objective: To investigate the neurotoxic properties of alpha-synuclein (α-Syn) aggregation in different buffers including PBS, SBF and Tris on altered cell lines, SHSY5Y, SK-N-MC and…Brain iron levels in Parkinson’s disease by postmortem and MRI measurements: A systematic review and meta-analysis
Objective: In this study we performed a systematic review and meta-analysis aiming to understand PD-associated iron variations in all brain regions that have been examined,…
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