MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    A cognitive fMRI study of non-manifesting LRRK2 and GBA carriers

    A. Thaler, N. Bregman, A. Mirelman, T. Gurevich, M. Gana-Weiss, A. Orr-Urtreger, T. Hendler, N. Giladi (Tel-Aviv, Israel)

    Objective: To assess the cognitive profile of non-manifesting carriers of GBA and LRRK2 mutations using two fMRI tasks: a Stroop interference and N-Back working memory…
  • 2016 International Congress

    Does cognitive decline contribute to poorer quality of life in incident Parkinson’s disease? A three year follow up

    R.A. Lawson, A.J. Yarnall, G.W. Duncan, D.P. Breen, T.K. Khoo, C.H. Williams-Gray, R.A. Barker, D. Collerton, J.P. Taylor, D.J. Burn (Newcastle upon Tyne, United Kingdom)

    Objective: To investigate the impact of cognition and cognitive decline on quality of life (QoL) in an incident Parkinson's disease (PD) cohort over three years.…
  • 2016 International Congress

    The practicalities of freezing of gait assessment methods

    C. Stummer, E. Mallia, B. Debû, B.R. Bloem, M.U. Ferraye (Nijmegen, Netherlands)

    Objective: To highlight the available assessment tools and to provide practical, experience-based recommendations for reliable assessment of freezing of gait (FOG). Background: FOG is a…
  • 2016 International Congress

    Real world conversion of levodopa to a novel extended release levodopa preparation: Determining predictors and dose ratios

    W. Ondo, P. Coss, M. Christie (Houston, TX, USA)

    Objective: To determine predictors of response and conversion ratios for a novel extended release levodopa preparation. Background: A new extended release levodopa preparation, Rytary®, has…
  • 2016 International Congress

    Altered resting-state functional interhemispheric connectivity in Parkinson’s disease

    X. Dan, S. Lin, A. Liu, Z. Wang, M.J. McKeown, P. Chan (Beijing, People's Republic of China)

    Objective: To examine direct interhemispheric functional connectivity (FCi) in Parkinson's disease (PD) during resting-state fMRI and to investigate the relations between observed connectivity changes and…
  • 2016 International Congress

    The role of striatal dopaminergic terminals in early de novo PD patients with speech impairment

    S. Polychronis, G. Pagano, M. Politis (London, United Kingdom)

    Objective: To assess the role of striatal dopaminergic terminals in early de novo (untreated) Parkinson's disease (PD) patients with impairment of speech. Background: Dopamine has…
  • 2016 International Congress

    Dopaminergic and metabolic network activities in onset-related subtypes of Parkinson’s disease: A dual-tracer positron emission tomography study

    F.T. Liu, J.J. Ge, J.J. Wu, Z.T. Ding, C.T. Zuo, J. Wang (Shanghai, People's Republic of China)

    Objective: The current study investigated the differences of dopaminergic and metabolic patterns between the young-onset subtype of Parkinson's disease (YOPD) and the late-onset subtype (LOPD)…
  • 2016 International Congress

    Relationship between freezing and pedunculopontine nucleus’ size in Parkinson’s disease: Semi quantitative analysis based on MRI with modified FGATIR sequence

    S. Chen, M. Tir, P. Monet, J.M. Constans, O. Godefroy, M. Lefranc, P. Krystkowiak (Amiens, France)

    Objective: The aim of this study was to determine the possible relation between pedunculopontine nucleus' size (PPN) and occurrence of freezing in Parkinson's disease (PD).…
  • 2016 International Congress

    Suppression of dyskinesia in Parkinson’s disease by electrical stimulation of dorsal subthalamic nucleus tissue

    H.A.C. Wark, G.H. Duffley, C.R. Butson, L.E. Schrock (Salt Lake City, UT, USA)

    Objective: The objectives of this study were to investigate suppression of dyskinesia in Parkinson's disease (PD) patients who had previously undergone deep brain stimulation (DBS)…
  • 2016 International Congress

    Impact of chronic LD treatment on metabolism, blood flow and blood-brain barrier permeability in the 6-OHDA rat model

    R.P. Lerner, Z. Bimpisidis, V. Jourdain, T. Chaly, M. Hellman, K. Graf, V. Dhawan, S. Dewey, A. Cenci, D. Eidelberg (Manhasset, NY, USA)

    Objective: To determine the effects of chronic LD treatment and induction of dyskinesias on cerebral metabolism, blood flow and blood-brain barrier permeability in 6-OHDA rat…
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