Identification of a trehalose treatment regimen with potential to be translated into a therapeutic for the treatment of Parkinson’s disease
Objective: To evaluate the preclinical efficacy of trehalose and to identify a dosing regimen that can be used to clinically evaluate trehalose as a disease-modifying therapy…Role of Apocyanin in modulating glial cell functions and associated inflammatory response in Lipopolysaccharide induced Parkinson’s disease model.
Objective: To explore the effect of apocyanin on glia mediated inflammatory response and α-synuclein aggregation in single intranigral LPS induced PD model Background: Converging lines…Mild cognitive impairment in newly diagnosed Parkinson’s disease: a three year follow up
Objective: To evaluate the stability of mild cognitive impairment in Parkinson’s disease (PD-MCI) over time to determine its clinical utility as a marker of disease.…Ghrelin and the IGF-1 axis in cognitive impairment in PD
Objective: To explore the association of acyl-ghrelin (AG) levels with cognitive impairment (CI) in PD Background: Unintended weight loss (UWL) in PD is associated with…Global inhibitory control in PD is impaired ON dopaminergic medication but not ON STN-DBS
Objective: The aim of our study is to obtain a better understanding of how DA and STN-DBS modulate basal ganglia (BG) pathway functions. Background: Patients…Prediction of cognitive progression in Parkinson’s disease using three cognitive screening measures
Objective: To assess the utility of commonly used cognitive screening tools in predicting the transition to mild cognitive impairment (MCI) and/or dementia (PDD) in Parkinson’s…Decision making under uncertainty in medicated and un-medicated Parkinson’s disesase
Objective: To evaluate decision making under risk in Parkinson’s disease patients, both medicated and un-medicated states probing constituent cognitive operations driving choice. Background: Prior literature…Comparison of the non-motor symptom assessment scale between LRRK2 G2019S positive versus matched control Parkinson disease
Objective: To compare the non-motor symptom assessment scale (NMSS) score between Leucine-rich repeat kinase 2 (LRRK2) mutation carriers with Parkinson disease (PD) and matched controls with…How common are the genomic rearrangements among possibly autosomal recessive PD cases in Turkey?
Objective: In this study, we aimed to investigate the frequency and phenotypical features in a subset of early-onset Parkinson’s disease (EO-PD) (age-at-onset ≤45 years) patients due…Association analyses of three susceptibility loci for Alzheimer’s disease in Parkinson’s disease, amyotrophic lateral sclerosis, and multiple system atrophy
Objective: Considering the overlapping of clinical manifestation and pathologic characteristics of Alzheimer’s disease (AD) and Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and multiple system…
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