Domain-specific impact of cerebral white matter hyperintensities on Parkinson’s disease cognitive functioning
Objective: In this study, we investigate the relationship between white matter hyperintensities (WMH) and Parkinson's disease (PD) cognitive impairment using a comprehensive neuropsychological battery with…Subjective cognitive decline reflects recent cognitive change in non-demented patients with Parkinson’s disease
Objective: We investigated whether subjective cognitive decline (SCD) can reflect recent cognitive change in patients with Parkinson’s disease (PD) who had shown non-demented cognitive performance…White matter microstructural damage as predictor of cognitive decline in Parkinson’s disease
Objective: To investigate patterns of cortical and white matter (WM) changes associated with progression to mild cognitive impairment (MCI) or dementia in patients with Parkinson’s…Assessing the response to L-dopa/carbidopa intestinal gel infusion (Deudopa) based on genetic status.
Objective: To asses genetic impact on dosage of L-dopa/carbidopa treatment Background: L-dopa/carbidopa intestinal gel infusion (LCIG) is a method of continuous dopaminergic stimulation used in…eEF1A2 promotes cell survival and protects against MPP+-induced apoptotic neuronal death through the PI3K/Akt/mTOR pathway
Objective: To assess the correlation of eEF1A2 and PI3K/Akt/mTOR expression and investigate the pro-survival role of eEF1A2 in NG108-15 rodent neuroglioma cells. Background: Eukaryotic protein…Exome sequencing in patients with impulse control disorders in Parkinson’s disease: a pilot study
Objective: To identify genetic variants associated with impulse control disorders (ICD) in Parkinson’s disease (PD) Background: ICD is frequently associated with dopamine agonist (DA) therapy…Alterations in lipid metabolism modify GBA1-mediated neurodegeneration in a Drosophila model of Parkinson’s disease
Objective: To understand how glucocerebrosidase (GBA1) mutations increase susceptibility to Parkinson's disease (PD). Background: Our understanding of the pathogenesis PD remains limited, and currently no…Longitudinal analysis of the relation of dopamine agonist use with impulse control disorders in Parkinson’s disease
Objective: To investigate the longitudinal relationship between dopaminergic therapies and impulse control disorders (ICD) in PD. Background: ICD are frequently associated with dopaminergic therapy, particularly dopamine…Predictive Ability of Clinical Timed Tests for Postural Instability and Gait Difficulty in Parkinson’s Disease
Objective: To identify clinical determinants for postural instability and gait difficulty in persons with Parkinson's disease (PD). Background: Gait deficits and postural instability in persons…Sports or no sports – is that the question in PD?
Objective: A multitude of risk factors or protective factors in developing Parkinson’s Disease (PD) are under discussion, as caffeine consumption or smoking .. Background: Frequent physical activity…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.