Piperine potentiate the neuroprotective effect of quercetin against MPTP induced neurotoxicity in rats
Objective: (1) Quercetin is well tolerated bioflavonoid used as supplement for various disorders but problem is its low oral bioavailability and (2) Piperine is combined…Brainstem reflexes in patients with neuroleptic-induced akathisia
Objective: We aimed to investigate brainstem reflexes in patients with akathisia. Background: Akathisia is characterized by urge, inner restlessness and constant movement of predominantly lower…Feasibility of utilizing the NIH Toolbox in Parkinson’s disease subjects with deep brain stimulation
Objective: To determine the feasibility of utilizing the NIH Toolbox in moderate to advanced disease Parkinson’s disease (PD) subjects with bilateral subthalamic nucleus deep brain…Predict cognitive decline with non-clinical markers in Parkinson’s disease
Objective: In this study, we investigated whether [123I]FP-CIT single photon emission computed tomography (SPECT) imaging measures and CSF marker profiles predict CI in PD patients…A new psychosocial intervention for people with Parkinsonian dementias: Adherence, barriers and facilitators
Objective: To investigate participant adherence and engagement to a home-based, companion-guided cognitive stimulation therapy adapted for people with Parkinsonian dementias (CST-PD). Background: Adherence to rehabilitation…Cognitive function and impulsive-compulsive behaviors in Parkinson’s disease motor subtypes
Objective: To investigate the differences in cognitive function between tremor-dominant (TD) and akinetic-rigid (AR) subtypes of Parkinson disease (PD). Background: Higher rates of dementia, autonomic symptoms,…Higher risk of cognitive impairment in Parkinson’s disease with comorbid diabetes
Objective: To determine the risk of cognitive impairment in individuals with Parkinson’s disease (PD) and diabetes. Background: Diabetes is associated with risk of cognitive impairment…Cognitive impairment in early onset and familial Parkinson’s disease.
Objective: The Parkinson’s Families Project (PFP) is a large-scale cohort of early onset (symptom onset <45) and familial Parkinson’s disease (PD) patients. One aim of…Rare variant analysis of the PPMI dataset to uncover the complex genetic architecture of Parkinson’s disease
Objective: To unravel the genetic factors that play a role in PD we used the whole exome sequencing data available as a part of Parkinson…A member of the HSP40/DNAJ family is a novel gene for early-onset parkinsonism
Objective: We aim to implicate novel genes/mutations using whole-exome sequencing (WES) in selected pedigrees. Background: Mutations have been identified in only 30% of familial parkinsonism.…
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