123I-FP-CIT SPECT imaging in early PD patients versus mid and late onset PD: Longitudinal data from the PPMI study
Objective: To determine whether there are longitudinal differences in dopaminergic denervation [as exemplified by signal reduction in 123I-FP-CIT SPECT] in early PD patients versus mid…Validation of the PREDIGT Score for the Incidence Rate of Parkinson disease
Objective: To assess the discriminative power of the PREDIGT formula for incident Parkinson disease (PD). Background: The inability to predict the incidence rate of PD…High intensity interval training elevates circulating BDNF and miRNAs level in patients with idiopathic Parkinson’s disease
Objective: To investigate if twelve weeks of high intensity interval training (HIIT) can enhance serum BDNF and miRNAs levels in patients with Parkinson’s disease (PD). Background: BDNF plays several important physiological functions including…Parkinson’s disease-associated mutations of PLA2G6 alters the membrane dynamics and α-synuclein stability
Objective: To investigate the mechanism of α-synuclein (α-Syn) aggregation. Background: PLA2G6 has been isolated as the gene responsible for an autosomal recessive form of Parkinson’s…Glabellar tap predicts dopamine transporter deficiency in parkinsonism
Objective: The objective of this study was to investigate the association between glabellar tap findings with nigrostriatal dopamine function in patients with unclear parkinsonism. Background:…Comorbid Parkinson’s disease in a Korean patient with Alexander’s disease
Objective: We report a unique case of genetically diagnosed Alexander's disease comorbid, with clinically diagnosed Parkinson's disease. Background: Alexander disease is a neurological disease, that causes…Levodopa-carbidopa intestinal gel infusion: a video analysis of long-term effect on gait and posture
Objective: To investigate the long-term effect of levodopa-carbidopa intestinal gel (LCIG) on gait and posture by means of both clinical and objective measures in Parkinson’s…Cortical thickness analysis in Parkinson’s disease with urinary symptoms
Objective: This study aimed to identify the significant region which can be related to urinary symptoms in Parkinson’s disease using correlation analysis between non-motor symptoms…Awareness of Levodopa/Carbidopa spacing with meals in patients of Idiopathic Parkinson’s disease – Insights from an Indian Parkinson’s Registry
Objective: Food interferes with gastrointestinal absorption of levodopa which requires spacing with meals. Study evaluated how many patient were spacing levodopa correctly, its effect on…Posterior cortical atrophy (PCA) attributable to corticobasal degeneration
Objective: Introduction: PCA is a clinico-radiological syndrome characterized by progressive decline in visual processing and other posterior cognitive functions, relatively intact memory and language in…
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