Incidence of drooling in Parkinson’s Disease and Impact on Quality of Life
Objective: The project aimed to determine the frequency and severity of drooling in the Parkinson’s Disease (PD) population in Cardiff & the Vale Health-board through…Monitoring Parkinson’s disease symptoms during daily life: A feasibility study
Objective: This study explores the feasibility of a newly developed multimodal monitoring system, which aims to measure PD symptoms during daily life by combining wearable…Ocular Motor Dysfunction as the Predictable Milestone of Life Prognosis in Progressive Supranuclear Palsy
Objective: The purpose of this study was to identify which symptoms predict the life prognosis in progressive supranuclear palsy (PSP). Background: Patients with PSP are…Biomarkers of the Level of Cognitive Impairment (CI) in patients with Parkinson’s Disease (PD): MRS study
Objective: The concentrations of NAA, Cr, mIns, and Glx are identified as putative neurochemical markers of CI in patients with PD. Background: On the basis…Beneficial and protective effects of Terminalia chebula in a murine model of Parkinson’s disease
Objective: Present study was designed to investigate whether Terminalia chebula (TC) extract would prevent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced neurotoxicity in male Wistar rats. Background: Parkinson's disease (PD)…Corneal confocal microscopy: An imaging biomarker of neurodegeneration in Parkinson’s disease
Objective: The aim of the study is to investigate whether corneal confocal microscopy (CCM) can be used as a rapid, reliable, automated and non-invasive method…Automated Metabolic Pattern Analysis in the Differential Diagnosis of Parkinsonism in a Swedish Cohort
Objective: To assess the accuracy of an automated, disease-specific, pattern model to distinguish among PD, MSA and PSP, in comparison with the final clinical diagnosis.…Exploratory Analysis of Electrocortical Signal Complexity in Patients with Progressive Supranuclear Palsy and Corticobasal Degeneration
Objective: We evaluated self-similarity of electrocortical activity as expression of brain signal complexity in patients clinically affected by Progressive Supranuclear Palsy (PSP) and Corticobasal Degeneration…Efficacy, Safety, and Tolerability of Supratherapeutic Doses of Apomorphine Sublingual Film for the Treatment of “OFF” Episodes in Patients With Parkinson’s Disease
Objective: To evaluate efficacy, safety, and tolerability of supratherapeutic doses of apomorphine sublingual film (APL-130277; APL) in patients with Parkinson’s disease (PD) and “OFF” episodes.…DCM extract of Scutellaria Pinnatifida modulate alpha-synuclein fibrillation and protects dopaminergic SH-SY5Y cells against rotenone
Objective: The aim of this study is to evaluate the effect of Dichloromethane extract (DCMex) of Scutellaria Pinnatifida (S) on of alpha-synuclein (ASN) and effect…
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