DNA Methylation is associated with gene expression changes in sporadic Parkinson Disease in the PPMI cohort.
Objective: To compare baseline whole blood DNA methylation in unmedicated sporadic Parkinson Disease (sPD) and healthy control (HC) participants from PPMI. To evaluate whole blood…Network analysis of brain perfusion in [11C]UCB-J PET: Parkinson’s related motor pattern (PDRP)
Objective: The aim was to investigate the use of R1 (relative delivery parameter) as a surrogate of blood perfusion to identify brain networks specific to…SpeechATAX: A rater blinded randomized controlled trial of intensive home-based biofeedback therapy for dysarthria in progressive ataxia
Objective: To investigate the effectiveness of a digitized intensive home-based speech rehabilitation, SpeechATAX, in people with progressive hereditary ataxia. Background: The loss of the ability…Detecting Changes in Parkinson’s Motor Symptom Patterns Using Wearable Devices
Objective: Evaluate mobile application and wearable device for detecting clinically significant changes in Parkinson's motor symptoms. Background: Monitoring motor and non-motor symptoms in Parkinson's disease…Gender differences in non-motor fluctuations in Parkinson’s disease
Objective: To estimate the burden of NMF in PD patients and to evaluate the possible gender effect. Background: Non-motor symptoms (NMS) are commonly experienced by…Incidence and Predictors of Axial Postural Abnormalities in Parkinson disease: data from the PPMI cohort
Objective: We aim to evaluate the incidence of axial postural abnormalities in patients with Parkinson’s disease (PD) and analyze their demographic and clinical predictors. Background:…Preliminary results of the validation study of the Shame in Parkinson’s disease (SPARK) Scale
Objective: The goal of this study is to validate the Shame in PARKinson’s disease (SPARK) Scale [1] which identifies the presence, the extent and some…Pronounced Cervical Dystonia in Ataxia with Vitamin E Deficiency
Objective: Objective: To describe a case report of an atypical phenotype of ataxia with vitamin E deficiency (AVED) and marked cervical dystonia. Background: Background: AVED…Atypical parkinsonism syndromes: clinical presentations
Objective: Here, our aim was to identify the characteristics of atypical clinical presentations of atypical parkinsonism syndromes in our cohort and our secondary aim was…Validity and responsiveness of the EQ-5D-3L in Friedreich-Ataxia
Objective: The objective was to validate the well-established EQ-5D in Friedreich’s ataxia (FA). Background: Health-related quality of life (HRQoL) is increasingly researched in FA. The…
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