Identification of Pre-Diagnostic Biomarkers for Parkinson’s Disease from Plasma Proteome
Objective: To identify pre-diagnostic biomarkers for Parkinson’s Disease (PD) from the plasma proteome. Background: The plasma proteome is a non-invasive and accessible measure to assess…Safety and Tolerability of Bemdaneprocel in People With Parkinson’s Disease: Results up to 24 Months From a Phase 1 Study
Objective: To report the safety and tolerability of bemdaneprocel in participants with Parkinson’s disease (PD) up to 24 months post transplantation. Background: Bemdaneprocel is an…Neuroimaging Factors Differentially Associated with Pathology and Clinical Presentation
Objective: Examine utility of a factor analysis approach to neuroimaging data in Lewy body disease (LBD) and Alzheimer’s disease (AD). Background: Significant heterogeneity exists among patients…Mitochondrial Complex I Brain Imaging in Parkinson’s Disease and Lewy Body Dementia
Objective: To compare brain mitochondrial respiratory Complex-1 (mito-C1) between Parkinson’s disease (PD) and PD dementia/Dementia with Lewy Bodies (PDD/DLB) participants and unimpaired controls, using 18F-BCPP-EF,…First in vivo evidence of the role of the noradrenergic system in olfactory dysfunction in Parkinson’s disease
Objective: To investigate the relationship between in vivo noradrenergic markers and olfactory impairment in patients with Parkinson’s disease (PD). Background: Degeneration of the noradrenergic (NA)…Associations Between Striatal Dopamine Transporter Binding and Motor Asymmetry In De Novo PD with and Without RBD
Objective: To evaluate the associations between striatal and motor asymmetry in Parkinson’s disease with probable RBD compared to without. Background: Parkinson’s disease is typically characterized…Severity of Motor Symptoms Correlates with Asymmetric Changes in Globus Pallidus Internus and Caudate Nuclei in Parkinson’s Disease
Objective: Explore the relationship between MDS-UPDRS motor sub-scores (MDS-UPDRS-III) and cerebral perfusion in different Regions of Interest (ROI) in patients with Parkinson’s disease (PwP). Background:…Functional Connectivity Changes Associated with Interlimb Coordination Force Deficits in Parkinson’s Disease
Objective: To investigate differences in the functional connectivity of motor regions between individuals with and without Parkinson’s disease (PD) during a force task requiring coordination…Mapping Cholinergic Signaling in Parkinson Disease Using [18F]VAT
Objective: To determine how cholinergic signaling changes within Parkinson Disease (PD) and how these differences relate to the progression of cognitive and behavioral symptoms. Background:…Emergency pallidotomy in a patient with chorea paralytica in primary hypoparathyroidism
Objective: To describe the management of patient with calcium disequilibrium presenting with a complex, hyperkinetic, movement disorder emergency akin to chorea paralytica, which was refractory…
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