Responders to a Highly Challenging Balance and Gait Intervention in People with Parkinson’s Disease
Objective: To characterize responsiveness to a highly challenging balance and gait intervention (HiBalance) in participants with Parkinson's disease (PD). Background: Exercise potentially improves gait, balance,…Balance evaluation and vestibular rehabilitation in patients with Hereditary Spastic Paraplegia – randomized clinical trial
Objective: This study aimed to assess balance and vestibular rehabilitation using virtual reality (VR) in patients with Hereditary Spastic Paraplegias (HSP). Background: HSP constitute a…Alexander technique remote-delivery group course for people living with Parkinson’s improves motor plan assembly time with correlated improvement in function
Objective: Alexander technique (AT) is a mind-body training that links inhibition, body schema, proprioception, and goal awareness to increase agency and enhance daily function. We…Possible Sarcopenia and its Association with Physical Activity among Parkinson’s disease Patients
Objective: This study aimed to screen the prevalence of possible sarcopenia and its association with physical activity level in a sample of PD patients. Background:…The Impact of Deep Brain Stimulation on the Embarrassment and Self-Esteem of Patients with Essential Tremor
Objective: To examine how Deep Brain Stimulation (DBS) influences embarrassment and self-esteem in patients with essential tremor (ET) and assess caregiver impressions. Background: Social embarrassment…The AIMS Clinic Model: A Retrospective Analysis of Interdisciplinary Neuropalliative Care for People with Advanced Parkinsonism
Objective: To describe and evaluate the Advanced Interdisciplinary Movement Disorders Supportive Care (AIMS) Clinic, a novel interdisciplinary clinic for patients with advanced movement disorders. Background:…SAGE-324/BIIB124, an investigational GABAA receptor PAM, for treatment of essential tremor
Objective: KINETIC2 is a multicenter, randomized, placebo-controlled, dose-response Ph2b study evaluating SAGE-324/BIIB124 for treatment of essential tremor (ET). Background: ET is a common movement disorder1,2…A Randomized, Double-blind, Phase 2a Clinical Trial to Study the Efficacy and Safety of Lamotrigine for Treatment of Patients with Dementia with Lewy Bodies
Objective: This proof-of-concept clinical trial will test the efficacy and safety of lamotrigine compared to placebo in patients with dementia with Lewy bodies (DLB). Background:…A Prospective, Multicenter, Single-Arm Feasibility Study Examining ECAP-Controlled, Closed-Loop Spinal Cord Stimulation for Parkinson’s Disease (eCAP-PD): Technical and Design Considerations
Objective: Conduct a prospective feasibility study to determine the effects of ECAP-controlled closed-loop spinal cord stimulation (SCS) on motor symptoms in Parkinson’s disease (PD) patients.…Pharmacological neuromodulation with intracerebroventricular administration of anaerobic dopamine for Parkinson’s disease
Objective: To assess the continuous intracerebroventricular (i.c.v.) of A-dopamine in patients with a telemetry-controlled intra-abdominal pump system connected to a subcutaneous catheter implanted through the…
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