Effect of Tactile Cueing on Dual Task Performance in Parkinson’s Disease-A Systematic Review and Meta-Analysis
Objective: This systematic review and meta-analysis were performed to examine the effect of tactile cueing on dual task (DT) performance in adults with idiopathic Parkinson’s…Adherence and Persistence Among Patients with Parkinson’s Disease Initiating Istradefylline: 12-Month Follow-Up from US Real-World Data
Objective: To evaluate 12-month adherence and persistence and identify factors associated with persistence among Parkinson’s disease (PD) patients initiating istradefylline, the first non-dopaminergic adjunct targeting…Characterising early morning akinesia and off (EMO) using Parkinson’s kinetigraph: analysis from a two centre national database in Parkinson’s disease .
Objective: Could wearable sensors such as Parkinson’s kinetograph (PKG) may provide valuable overnight data to detect EMO to augment care in clinic. Background: Early morning…Gender Differences Following Bilateral STN DBS Surgery in Parkinson’s Disease
Objective: To examine DBS surgery outcomes within the Deep Brain Stimulation (DBS) PD cohort at the NIH among males and females and improve our understanding…Antipsychotic Prescriptions Among Nursing Home Residents with Parkinson’s Disease in the End-of-Life Period
Objective: To determine whether antipsychotic prescriptions differ between community-dwelling and nursing home residents with PD in the last 6 months of life. Background: Most antipsychotics…Neuronal Exosome based markers in Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: This study aimed to explore cellular inflammatory and autophagic mediators in neuronal exosomes of PD and PSP. Background: Parkinson’s disease (PD) is a common…Dysregulated Anti-Viral Response in LRRK2 Mice Following Infection with H1N1 Influenza Induces DA Neuron Loss in the SNpc.
Objective: In this study, we sought to determine if there is a synergistic effect of non-neurotropic H1N1 influenza and the G2019S LRRK2 mutation associated Parkinson’s…Serum levels of VEGF-C and ENDGLIN in Parkinson’s disease and their clinical relevance
Objective: To evaluate the differences in serum concentrations of neurovascular unit (NVU)-related cytokines between patients with Parkinson's disease (PD) and control subjects (Ctr) and to…LRRK2 I1371V Mutation: Unraveling Pathogenic Mechanisms in Dopaminergic Neurons via Membrane Fluidity & Calcium Dysregulation using PD Patient iPSCs
Objective: To estimate pathogenicity of LRRK2 I1371V mutation in PD patient iPSC-derived DA-neurons & assess underlying disease mechanisms involving membrane fluidity, Ca2+ dysregulation, & Rab8A/Rab10…Ultrasound of Spinal Fluid Dynamics in Headache and Vertigo Patients with Central Sensitization: Novel Biomarker
Objective: This study aimed to investigate the neurophysiological responses and potential mechanisms underlying the therapeutic effects of ultrasound (US)-guided dry needling in patients presenting with…
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