Two parallel nigrostriatal subcircuits mediate the arousal effect of dopaminergic neurons in substantia nigra pars compacta
Objective: This study systematically investigates the involvement of dopaminergic (DA) neurons in substantia nigra pars compacta (SNc) in wakefulness-sleep regulation and explores the underlying circuit…Dysphagia is Frequent in early Parkinson´s Disease. Results from a 5-year Follow-up Study.
Objective: The aim of the present study was to analyze the frequency of dysphagia in patients with early Parkinson´s disease (PD) and to compare with…TRPV1: A Potential Therapeutic Target for Inflammation and Pain in Parkinson’s Disease
Objective: Unveiling the Pain Mechanism in Parkinson's Disease: A Path to New Therapies Background: Parkinson's disease (PD) are well-known movement disorder. While motor symptoms are…Association of Autonomic Symptoms with Motor Features of Parkinson’s Disease in the Nigeria Parkinson’s Disease Research Network Registry
Objective: To determine the profile of AS and the relationship to motor severity and phenotype in persons with PD in Nigeria. Background: Autonomic symptoms (AS)…RBD Unmasked: LRRK2 and the Prodromal Path to Parkinson’s Disease
Objective: The primary objective is to analyze and compare the prevalence of RBD in LRRK2-positive individuals across different stages, including healthy controls (HC), prodromal Parkinson's…The Association of Pain with motor symptom severity in Parkinson’s Disease: A secondary data analysis
Objective: This study investigates the association between pain and motor symptom severity (MSS) in PD patients. Background: Parkinson's Disease (PD) is the second most common…Subjective Sleep Quality and Pathological Sleepiness in Veterans with Parkinson’s Disease
Objective: To determine the subjective sleep quality and its association with pathological sleepiness in Veterans with Parkinson's disease (PD). Background: Sleep quality issues and pathological…Apathy in de novo Parkinson’s disease improves after the first years with dopaminergic treatment.
Objective: to define the evolution of apathy and other neuropsychiatric symptoms in patients with early Parkinson’s disease (PD). Background: Apathy is a common neuropsychiatric symptom…Cognitive load in a diagnostic electrophysiologic assessment of functional tremor.
Objective: To substantiate a rationale for cognitive load (CL) assessment to differentiate functional tremor (FT) and organic tremor (OT) in the electrophysiologic study. Background: FT…Bistriatal hypermetabolism on 18-FDG PET-CT in tardive dyskinesia
Objective: Tardive dyskinesia (TD) describes various movement disorders developing after treatment with dopamine receptor blocking agents (DRBA), including stereotypy, akathisia, dystonia, tremor, tics and chorea.…
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