Early Impairment in the Immunomodulatory Function of Mesenchymal Stromal Cells Contributes to Heightened Peripheral and Neuroinflammation in Parkinson’s Disease Insights From In Vivo Chronic PD Rat Model and In Vitro PD iPSC Model
Objective: To assess the timeline dependent changes in endogenous Bone-Marrow-Mesenchymal-Stromal-Cells (BMMSC) in in-vivo chronic PD model and validating these cellular modifications in human iPSC derived…The Bjorn Moller Research Repository: A Resource for Movement Disorders Research
Objective: To build a repository of longitudinally collected biological samples and clinical, demographic, and lifestyle data from individuals with Parkinson’s disease (PD) and other movement…Brain Energetics: Changes in Healthy Aging and Parkinson’s Disease
Objective: To identify in vivo bioenergetic alterations in healthy aging and Parkinson’s disease (PD). Background: PD-related cerebral metabolic alterations have been robustly characterized [1] and…Influence of Gut Microbiota-Derived TMAO on Disease Severity in Parkinson’s Disease
Objective: This study aims to investigate how gut microbiota composition influences trimethylamine N-oxide (TMAO) levels in PD patients and whether TMAO and gut microbiota composition…Comparison of MIBG Uptake in the Major Salivary Glands Between Rapid Eye Movement Sleep Behavior Disorder and Parkinson’s Disease
Objective: This study aimed to evaluate 123I-metaiodobenzylguanidine (MIBG) uptake in the major salivary glands (MSG) in patients with rapid eye movement sleep behavior disorder (RBD)…Longitudinal MRI Study of Hippocampal Subfields Morphometry in Early Parkinson’s Disease
Objective: This prospective cohort study longitudinally investigated hippocampal subfield shape deformation and atrophy in early-stage Parkinson’s Disease (PD), using spherical harmonic-based shape analysis. Background: Hippocampal…Impact of Patient-Specific Structural Connectivity of STN-DBS on Balance and Mobility – Pilot study
Objective: To evaluate the impact of patient-specific structural connectivity between VTA in STN targeting and SMA/preSMA on functional mobility improvements in PD patients undergoing DBS.…Description Genotype/phenotype of patients with Parkinson’s disease. Report of an Argentinean cohort included in the LARGE PD Consortium.
Objective: To characterize the genetic and phenotypic profile of Argentinean Parkinson's patients and contribute to the understanding of the genetic heterogeneity of this disease. Background:…Assessing the potential association of rs2298383 in ADORA2A as a predictor of Levodopa-Induced Dyskinesia in Latin American Parkinson’s Disease patients
Objective: To analyze the association between ADORA2A-rs2298383 and levodopa induced dyskinesias (LID) in a cohort of Latin American Parkinson’s disease patients. Background: Previous evidence has…Prevalence and Characteristics of Glucocerebrosidase Genetic Variants in Nepalese Early-onset Parkinson’s Disease Patients
Objective: To evaluate the genotype and phenotype of early-onset Parkinson´s Disease (EOPD) in the Nepalese population. Background: A significant proportion of early-onset PD (EOPD) can…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.