2022 International Congress » Parkinson's Disease: Pathophysiology

Aerobic glycolysis regulates microglia-mediated neuroinflammation by promoting H3K9 lactylation in Parkinson’s disease

Q. Qixiong, W. Hengming, W. Danlei, L. Jingyi, Q. Yi, Z. Jingwei, L. Jiangting (wuhan, China)

Alteration of peripheral blood cell profiles in Parkinson’s disease: a retrospective case-control study

G. Tian, R. Zhou, X. Guo, R. Li (Xi'an, China)

Alteration of the fecal microbiota in Turkish patients with idiopathic Parkinson’s disease

GBY. Babacan-Yildiz, CZK. Kayacan, IK. Karacan, BS. Sumbul, BE. Elibol, OG. Gelisin, OA. Akgul (ISTANBUL, Turkey)

Anti-α-synuclein antibody 5G4 differentiates idiopathic REM Sleep Behavior Disorder patients from healthy controls in skin biopsies

S. Toth, K. Kulcsarova, E. Feketeova, J. Ventosa, M. Maretta, A. Kunova, M. Bekeova, P. Christova, J. Baloghova, E. Mechírová, Z. Gdovinova, M. Skorvanek (Kosice, Slovakia)

Associations between stimulation-induced gamma entrainment and motor signs of Parkinson’s Disease

M. Olaru, A. Hahn, J. Anso, C. Oehrn, J. Sermon, R. Bogacz, T. Denison, B. Duchet, S. Little, P. Starr (San Francisco, USA)

Blaming neuromelanin for Parkinson’s disease: time-dependent tyrosinase overexpression drives endogenous synucleinopathy in non-human primates

J. Lanciego, J. Chocarro, A. Fajardo-Serrano, A. Vazquez, AI. Rodriguez-Perez, J. Labandeira-Garcia, M. Vila, A. Rico (Pamplona, Spain)

Blood neurofilament light chain as a biomarker of Parkinson’s disease

S. Ganesh, B. Huxford, A. Zirra, C. Edwards, C. Simonet, T. Haque, D. Gallagher, C. Budu, R. Dobson, A. Noyce (London, United Kingdom)

Body-first and brain-first PD animal models mimic human PD subtypes

N. Vanden Berge, M. Pedersen, I. Klæstrup, J. Jacobsen, M. Simonsen, A. Alstrup, M. Romero-Ramos, P. Borghammer (Aarhus N, Denmark)

CCL5 promotes Th17 migrating into SNpc by promoting Th17 proportion increase and LFA-1 expression

XZ. Xue (WuHan, China)

Circadian cycle and disease phenotype in Parkinson’s disease, insights by motion sensors and molecular biology.

M. Marano, A. Casamassa, M. Rossi, A. Magliozzi, Z. Yekutieli, A. Vescovi, J. Rosati, V. Di Lazzaro (Rome, Italy)

Contribution of cognitive load to akinetic and trembling freezing of gait manifestations in patients with Parkinson’s disease

P. Ginis, N. D'Cruz, D. Zoetewei, T. Herman, M. Gilat, J. Hausdorff, A. Nieuwboer (Leuven, Belgium)

Contribution of external globus pallidus to motor deficits of Parkinson’s disease: optogenetic studies in murine model

S. Dibisceglie Caballero, A. Ces, F. Ambroggi, M. Amalric, A. Ouagazzal (Marseille, France)

Cortical oscillatory feature-based classification of Parkinson’s disease with freezing gait

A. Singh, S. Roy, KC. Santosh (Vermillion, USA)

Deep behavioural analysis of zebrafish models of Parkinson’s disease

TM. Tzotzolaki, J. Garcia Fernandez, F. de Santis, J. Terriente (Barcelona, Spain)

Delayed post-stroke parkinsonism: description of two cases and possible mechanism

T. Friedeman- Korn, M. Bauer, M. Abu Snineh, C. Weill, D. Arkadir (Jerusalem, Israel)

Determination of glycine transporter 1 levels with [3H]-NFPS binding in hemi-parkinsonian rats with L-DOPA induced dyskinesia

I. Frouni, D. Bédard, E. Kim, S. Belliveau, C. Kwan, P. Huot (Montreal, Canada)

Determination of metabotropic glutamate receptor 2/3 distribution with [3H]-LY-341,495 in Parkinson’s disease patients with visual hallucinations

D. Bedard, E. Kim, I. Frouni, P. Huot (Montreal, Canada)

Dopaminergic modulation of express reaching responses in Parkinson’s disease

M. Gilchrist, R. Kozak, B. Corneil, P. Macdonald (London, Canada)

Dried blood and plasma spots for the measurement of neurofilament light chain and inflammatory cytokines in patients with REM sleep behaviour disorder

B. Huxford, C. Simonet, L. Carbonell, A. Zirra, N. Vickaryous, A. Gill, A. Schrag, R. Dobson, A. Noyce (London, United Kingdom)

Effect of Aspartame on Parkinson’s Disease Progression and Severity

D. Kushigian, O. Vaou (Boston, USA)

Environmental factors and Parkinson’s disease

Y. Babajani, M. Salari, M. Afroozian, M. Etemadifar (Tehran, Islamic Republic of Iran)

FACIAL EMOTION EXPRESSIVITY IN PARKINSON’S AND ALZHEIMER’S DISEASES

A. Cannavacciuolo, A. Guerra, D. Colella, M. Salzillo, A. de Biase, G. Paparella, M. Canevelli, G. Bruno, A. Berardelli, M. Bologna (Pozzilli, Italy)

Fundamental changes in Nerve Conduction Velocity and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in a chronic PD in vivo model: a neurotool for Parkinson’s disease diagnosis

I. Datta, K. Mondal, A. Kaushal (Bengaluru, India)

Increased Neutrophil to Lymphocyte Ratio Distinguish Parkinson’s Disease and Parkinson Plus Syndrome

IH. Kwak, HI. Ma, YE. Kim (Anyang, Republic of Korea)

Inflammatory changes in subjects with de novo Parkinson’s disease

T. Yacoubian, A. Gerstenecker, Y. Fang, A. Amara, N. Stover, L. Ruffrage, C. Collette, R. Kennedy, Y. Zhang, H. Qin, E. Benveniste, J. Mcconathy, D. Standaert (Birmingham, USA)

Lower-limb dystonia as an explanation for freezing of gait responsive to cueing in Parkinson’s Disease

M. Dias, M. Soares (Lisbon, Portugal)

Metabolic Biomarkers of Parkinson’s Disease in Peripheral Tissue

L. Mischley, E. Shankland, S. Liu, S. Bhayana, D. Marcinek (Seattle, USA)

Methods of biochemical diagnosis early stage of Parkinson’s disaese in Uzbekistan

B. Kurbanov (Tashkent, Uzbekistan)

mGlu3 receptors in Parkinson’s disease as a candidate target for neuroprotective therapy: evidence from preclinical studies to human genetic.

M. Alborghetti, L. Di Menna, V. Bruno, G. Battaglia, FE. Pontieri, E. Bianchini, M. Simmaco, M. Borro, F. Nicoletti (Rome, Italy)

Microglial activation facilitates alpha synuclein propagation and neurodegeneration in αSyn preformed fibrils (PFF)-injected PD mouse model

YE. Kim, TT. Lai, F. Richter, HI. Ma (Anyang, Republic of Korea)

Molecular alterations and pathological remodeling of colonic wall in patients with Parkinson’s disease

G. Bellini, G. Palermo, D. Frosini, L. Benvenuti, C. Pellegrini, M. Bellini, N. Bernardini, M. Fornai, R. Ceravolo (Pisa, Italy)

Neurovascular and immune determinants of selective vulnerability of dopaminergic neurons in Parkinson’s Disease

T. Balzano, N. Lopez Gonzalez-Del-Rey, N. Esteban-Garcia, A. Reinares-Sebastian, I. Trigo-Damas, JA. Pineda-Pardo, C. Cavada, JA. Obeso, J. Blesa (Mostoles, Spain)

Non-apoptotic caspase-3 activation mediates early synaptic dysfunction of indirect pathway neurons in the parkinsonian striatum

C. Li, T. Fieblinger, E. Espa, MA. Cenci (Lund, Sweden)

Plasma biomarkers of disease progression in Parkinson’s disease

A. Lupini, N. Ashton, A. Pilotto, B. Battaglio, C. Zatti, S. Gipponi, E. Cottini, I. Grossi, A. Salvi, G. de Petro, M. Pizzi, K. Blennow, H. Zetterberg, A. Padovani (Brescia, Italy)

Prevalence and distribution of disease-associated alpha-synuclein in a homeless population

N. Visanji, K. Danics, G. Kovacs (Toronto, Canada)

Relationship between falls and motor state in Parkinson’s disease patients with motor fluctuations

Y. Okuma (Izunokuni, Japan)

Risk and Protective Substances among the Parkinson Disease Patients in Palembang Municipality

MRO. Odiesta, SM. Marisdina, EB. Bahar (Palembang, Indonesia)

SCFAs participate in the pathogenesis of Parkinson’s disease by regulating NLRP3 inflammasomes activation

Z. Mao, J. Xiong, Z. Min, Z. Xue (Wuhan, China)

Striatal Subregion Analysis Associated with REM Sleep Behavior Disorder in Parkinson’s disease

IH. Kwak, HI. Ma, YE. Kim, YJ. Kim (Anyang, Republic of Korea)

Structural connectivity affecting freezing of gait after globus pallidus internus deep brain stimulation in Parkinson’s disease

S. Lee, S. Jo, J. Lee, M. Kim, H. Lee, S. Chung (Seoul, Republic of Korea)

Synaptic Zn2+ Contribution to Parkinson’s Disease Pathophysiology: Pharmacological & Genetic Studies in Preclinical Mouse Models

AM. Ouagazzal, J. Sikora (Marseille, France)

Temporal segmentation of FOG using AFSD algorithm on RGB data and on walkway pressure data

M-K. Lu, Y-W. Wang, C-H. Tsai, T. Debusschere, K-C. Hsu (Taichung City, Taiwan)

The effect of short-term treadmill exercise in the alpha-synuclein preformed fibril rat model of Parkinson’s disease

S. Fleming, J. Patterson, C. Kemp, J. Lepp, E. Hamad, S. Scott, J. Holden, A. Davis, C. Szarowicz, J. Lipton, M. Kubik, N. Kuhn, A. Stoll, K. Luk, C. Sortwell (Rootstown, USA)

The prevalence of helicobacter pylori in Parkinson’s disease

N. Mansurova (Tashkent, Uzbekistan)

The relationship between sleep and Parkinson’s disease progression: A Mendelian Randomization study

E. Matar, M. Mahjoub (Sydney, Australia)

Utilising multiple murine models to investigate sleep and circadian system dysfunction in PD

N. Garner, P. Kim, M. Weiergräber, H. Oster, O. Rawashdeh (Brisbane, Australia)