Altered [18F]VAT Uptake Supports Cholinergic Dysfunction in Isolated Adult-Onset Cervical Dystonia
Objective: Our aim is to investigate whether altered cholinergic function is associated with isolated adult-onset cervical dystonia (CD). Background: Animal models and clinical observations suggest…Microbiota and Gastrointestinal Manifestations of Parkinson’s Disease with Arabic Translation of Gastrointestinal Dysfunction Scale
Objective: To investigate the frequency of occurrence of gastrointestinal tract GIT symptoms and their relation to patients’ clinical characteristics in addition the characteristics of gut…Cholinergic deficits in Parkinson Disease
Objective: To determine whether loss of cholinergic projections to cortical and limbic regions contributes to the development of dementia in Parkinson’s disease (PD). Background: PD…Cholinergic subtyping in Parkinson disease: differential 2-year interval changes
Objective: To investigate 2-yr interval change in cholinergic transporters in biology-based cholinergic subgroups using serial VAChT [18F]FEOBV brain PET in Parkinson’s disease (PD). Background: Current…Free water imaging of the cholinergic forebrain in body vs. brain-first Parkinson’s disease subtypes
Objective: To investigate the relationship between basal forebrain (BF) neurodegeneration and cholinergic system in body vs brain-first Parkinson’s disease (PD) subtypes. Background: Free water imaging…The comparison of curcumin and naringenin effects on motor function in rotenone model of Parkinson’s disease
Objective: The aim of the study was to compare the effects of curcumin and naringenin on rotenone-induced motor deficits and related neurochemical changes. Background: Experimental…The development of a multiplex allele specific PCR to improve the diagnostic yield of NGS in the GBA gene screening
Objective: Our aim is to offer a complete and reliable diagnostic service excluding false negative. Background: Heterozygous variants in the GBA gene are the most…Nucleus basalis of Meynert and total gray matter atrophy are related to cognitive and gait decline in Parkinson’s disease
Objective: To assess the associations between the nucleus basalis of Meynert (NBM) and total grey matter atrophy with cognitive phenotype and gait measures in a…Hesperidin ameliorates rotenone-induced Parkinson’s disease in mice via improving neuroinflammation and oxidative stress
Objective: The goal of the present study is to examine the neuroprotective property of hesperidin on rotenone-induced Parkinson's disease in mice. Background: The second most…Cholinergic topography and clinical profile of early Parkinson’s patients with GBA mutations
Objective: To explore the regional cholinergic innervation and clinical profile of early Parkinson’s disease (PD) patients carrying GBA mutations (GBA-PD). Background: The most common genetic…
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