Evaluation of apathy before and after subthalamic nucleus deep brain stimulation therapy in advanced Parkinson’s disease patients
Objective: Deep brain stimulation (DBS) has been approved to relieve the motor symptoms of Parkinson's disease (PD) patients when the optimal pharmachologic treatment is unsatisfactory.…Methylphenidate in Progressive Supranuclear Palsy [PSP] – Old drug, New Indications?
Objective: To evaluate whether Methylphenidate can improve some symptoms of PSP. Background: PSP is a neurodegenerative disorder with limited therapeutic options. Methylphenidate[MPH] , a drug…Microstructural changes in white and grey matter related to apathy, depression and anxiety in de novo Parkinson’s disease patients
Objective: To study microstructural changes in grey and white matter in early drug-naïve Parkinson's disease (PD) patients and correlate these changes with neuropsychological manifestations. Background:…Tractographically defined subthalamic connectivity is associated with apathy in Parkinson’s disease and healthy subjects
Objective: We aimed to study the baseline white matter characteristics of tractographically defined subthalamic connectivity using Diffusion Tensor Imaging in Parkinson's Disease patients and healthy…Microstructural Changes in Normal Appearing White Matter in Parkinson’s Disease (PD) Correlate with Motor, Tremor, and Neuropsychiatric Scores
Objective: To determine if microstructural changes in the normal appearing white matter of PD are associated with clinical manifestations of disease. Background: White matter (WM)…Distinct effects of apathy and dopamine on effort-based decision making in Parkinson’s disease
Objective: To determine if disrupted effort-based decision making (EBDM) underlies the syndrome of apathy in PD, and whether this disruption is modulated by the dopaminergic…The neural correlates of apathy in premanifest and manifest Huntington’s disease: A cross-sectional multimodal imaging study
Objective: To delineate the brain correlates of apathy severity by means of glucose metabolism (18-FDG PET), grey-matter (GM) and white-matter (WM; FA-DTI) changes and relations…Apathy in adolescents with Tourette syndrome (TS), more than a teenager attitude
Objective: To explore the presence of apathy in teenagers with TS. Background: TS is a complex neuropsychiatric disorder generally classified as a hyperkinetic disorder. Apathy…Neuroanatomical correlates of apathy in non-demented and non-depressed Parkinson’s disease
Objective: We aimed to explore the neuroanatomical correlates of isolated apathy in PD by means of voxel-based morphometry (VBM) analysis and its correlates with other…Anhedonia and its correlation with clinical aspects in Parkinson’s disease
Objective: The aim of this study is to evaluate the characteristics of anhedonia and its correlation with clinical aspects of PD in a relatively large…
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